Estimates of Type 2 Diabetes Mellitus Burden Attributable to Particulate Matter Pollution and Its 30-Year Change Patterns: A Systematic Analysis of Data From the Global Burden of Disease Study 2019.
Ying Wu, Rongguo Fu, Chen Lei, Yujiao Deng, Weiyang Lou, Li Wang, Yi Zheng, Xinyue Deng, Si Yang, Meng Wang, Zhen Zhai, Yuyao Zhu, Dong Xiang, Jingjing Hu, Zhijun Dai, Jie Gao
Author Information
Ying Wu: Department of Nephrology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Rongguo Fu: Department of Nephrology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Chen Lei: Department of Endocrinology, The General Hospital of Ningxia Medical University, Yinchuan, China.
Yujiao Deng: Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Weiyang Lou: Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Li Wang: Department of Nephrology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yi Zheng: Department of Nephrology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xinyue Deng: Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Si Yang: Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Meng Wang: Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhen Zhai: Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yuyao Zhu: Department of Nephrology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Dong Xiang: Celilo Cancer Center, Oregon Health Science Center affiliated Mid-Columbia Medical Center, The Dalles, OR, United States.
Jingjing Hu: Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States.
Zhijun Dai: Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Jie Gao: Department of Nephrology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Background: Epidemiological trends of type 2 diabetes mellitus attributable to fine particulate matter (PM) Pollution remain unclear. Here, we estimated spatiotemporal trends of type 2 diabetes mellitus burden attributable to PM Pollution, including ambient particulate matter Pollution (APMP) and household air Pollution (HAP), from 1990-2019. Methods: Data were obtained from the Global Burden of Disease Study 2019 and were analyzed by age, sex, year, and location. Joinpoint regression analysis was applied in the analysis of temporal trends in type 2 diabetes mellitus burden over the 30 years. Results: Globally, PM Pollution contributed to 292.5 thousand deaths and 13 million disability-adjusted life-years (DALYs) in 2019. APMP ranked third among all risk factors, causing an increase in type 2 diabetes mellitus burden from 1990, whereas the impact of HAP significantly fell during the same period. Both APMP and HAP contributed the most to deaths and DALYs of type 2 diabetes mellitus among older people. However, the age-standardized death and DALY rates of type 2 diabetes mellitus attributable to APMP were greater among males and people in the middle socio-demographic index countries, especially in Southern Sub-Saharan Africa. For HAP, type 2 diabetes mellitus burden was modestly higher in females and was highest in Oceania, which was the only region with an increase from 1990. Conclusions: PM Pollution resulted in substantial and increasing type 2 diabetes mellitus burden worldwide. Hence, governments and health systems should take steps to reduce air Pollution to mitigate this increasing burden.
