Functional and Psychological Changes after Exercise Training in Post-COVID-19 Patients Discharged from the Hospital: A PRISMA-Compliant Systematic Review.

Amir Hossein Ahmadi Hekmatikar, João Batista Ferreira Júnior, Shahnaz Shahrbanian, Katsuhiko Suzuki
Author Information
  1. Amir Hossein Ahmadi Hekmatikar: Department of Sport Science, Faculty of Humanities, Tarbiat Modares University, Tehran 14117-13116, Iran.
  2. João Batista Ferreira Júnior: Federal Institute of Sudeste of Minas Gerais, Rio Pomba 36180-000, Brazil. ORCID
  3. Shahnaz Shahrbanian: Department of Sport Science, Faculty of Humanities, Tarbiat Modares University, Tehran 14117-13116, Iran. ORCID
  4. Katsuhiko Suzuki: Faculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Saitama, Japan. ORCID

Abstract

Millions of people worldwide are infected with COVID-19, and COVID-19 survivors have been found to suffer from functional disabilities and mental disorders such as depression and anxiety. This is a matter of concern because COVID-19 is still not over. Because reinfection is still possible in COVID-19 survivors, decreased physical function and increased stress and anxiety can lower immune function. However, the optimal exercise intensity and volume appear to remain unknown. Therefore, the current systematic review aimed to evaluate the effect of resistance or aerobic exercises in post-COVID-19 patients after hospital discharge. We conducted searches in the Scopus, SciELO, PubMed, Web of Science, Science Direct, and Google Scholar databases. Studies that met the following criteria were included: (i) English language, (ii) patients with COVID-19 involved with resistance or aerobic exercise programs after hospital discharge. Out of 381 studies reviewed, seven studies met the inclusion criteria. Evidence shows that exercise programs composed of resistance exercise (e.g., 1-2 sets of 8-10 repetitions at 30-80% of 1RM) along with aerobic exercise (e.g., 5 to 30 min at moderate intensity) may improve the functional capacity and quality of life (reduce stress and mental disorders) in post-COVID-19 patients. In addition, only one study reported reinfection of three subjects involved with the exercise program, suggesting that exercise programs may be feasible for the rehabilitation of the patients. A meta-analysis was not conducted because the included studies have methodological heterogeneities, and they did not examine a control group. Consequently, the results should be generalized with caution.

Keywords

References

  1. Front Physiol. 2021 Mar 03;12:637590 [PMID: 33746777]
  2. Sports Med. 2017 Dec;47(12):2585-2601 [PMID: 28755103]
  3. J Clin Med. 2021 Sep 27;10(19): [PMID: 34640447]
  4. Br J Sports Med. 2020 Mar;54(6):341-348 [PMID: 29934430]
  5. J Sports Sci. 2017 Jun;35(11):1073-1082 [PMID: 27433992]
  6. Int J Rehabil Res. 2021 Mar 1;44(1):77-81 [PMID: 33323782]
  7. Prog Cardiovasc Dis. 2020 May - Jun;63(3):386-388 [PMID: 32220590]
  8. Crit Care Explor. 2021 Aug 19;3(8):e0516 [PMID: 34476403]
  9. BMJ. 2011 Oct 18;343:d5928 [PMID: 22008217]
  10. Iran J Public Health. 2020 Nov;49(11):2120-2127 [PMID: 33708732]
  11. J Sports Sci. 2021 Jan;39(1):101-107 [PMID: 32842905]
  12. Int J Surg. 2021 Apr;88:105906 [PMID: 33789826]
  13. Eur J Appl Physiol. 2002 Oct;87(6):506-8 [PMID: 12355189]
  14. Int J Environ Res Public Health. 2021 Apr 09;18(8): [PMID: 33918887]
  15. Am J Phys Med Rehabil. 2020 Oct;99(10):865-869 [PMID: 32732746]
  16. Diabetes Metab Syndr. 2018 Sep;12(5):661-666 [PMID: 29678607]
  17. Aging Clin Exp Res. 2021 Nov;33(11):2941-2952 [PMID: 33880736]
  18. JAMA Psychiatry. 2018 Jun 1;75(6):566-576 [PMID: 29800984]
  19. Eur J Sport Sci. 2021 Apr;21(4):636-645 [PMID: 32345132]
  20. Med Sci Sports Exerc. 2011 Jul;43(7):1334-59 [PMID: 21694556]
  21. Front Sports Act Living. 2020 May 15;2:61 [PMID: 33345052]
  22. MedComm (2020). 2021 Dec 16;2(4):838-845 [PMID: 34957469]
  23. J Med Virol. 2021 Jan;93(1):250-256 [PMID: 32592501]
  24. Arch Phys Med Rehabil. 2001 Feb;82(2):174-82 [PMID: 11239307]
  25. Arch Neurol. 2005 Jul;62(7):1113-7 [PMID: 16009768]
  26. Res Synth Methods. 2021 Jan;12(1):55-61 [PMID: 32336025]
  27. Scand J Med Sci Sports. 2014 Apr;24(2):414-21 [PMID: 22738284]
  28. J Frailty Aging. 2021;10(3):297-300 [PMID: 34105716]
  29. Calcif Tissue Int. 2013 Aug;93(2):101-20 [PMID: 23828275]
  30. Biomed Res Int. 2020 Sep 23;2020:3292916 [PMID: 33029503]
  31. Front Psychol. 2020 Oct 02;11:577684 [PMID: 33132986]
  32. Int J Mol Sci. 2020 Jun 30;21(13): [PMID: 32630032]
  33. Clin Rehabil. 2022 Jan;36(1):59-68 [PMID: 34344230]
  34. Eur J Neurol. 2021 Oct;28(10):3411-3417 [PMID: 32997370]
  35. Exp Gerontol. 2020 Feb;130:110787 [PMID: 31794851]
  36. Emerg Infect Dis. 2020 Jul;26(7):1618-1620 [PMID: 32197060]
  37. Lancet Public Health. 2021 Oct;6(10):e709-e719 [PMID: 34474014]
  38. Ann Med. 2018 Dec;50(8):675-693 [PMID: 30169116]
  39. BMJ Open Respir Res. 2021 Sep;8(1): [PMID: 34489236]
  40. Sports (Basel). 2021 Jan 11;9(1): [PMID: 33440732]
  41. J Int Soc Sports Nutr. 2018 Feb 27;15:10 [PMID: 29497353]

MeSH Term

COVID-19
Exercise
Hospitals
Humans
Quality of Life
SARS-CoV-2

Word Cloud

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