Predicting Success in the Embryology Lab: The Use of Algorithmic Technologies in Knowledge Production.

Alina Geampana, Manuela Perrotta
Author Information
  1. Alina Geampana: Department of Sociology and Policy, School of Social Sciences and Humanities, Aston University, Birmingham, United Kingdom. ORCID
  2. Manuela Perrotta: Department of People and Organisations, School of Business and Management, Queen Mary University of London, United Kingdom.

Abstract

This article analyzes local algorithmic practices resulting from the increased use of time-lapse (TL) imaging in fertility treatment. The data produced by TL technologies are expected to help professionals pick the best embryo for implantation. The emergence of TL has been characterized by promissory discourses of deeper embryo knowledge and expanded selection standardization, despite professionals having no conclusive evidence that TL improves pregnancy rates. Our research explores the use of TL tools in embryology labs. We pay special attention to standardization efforts and knowledge-creation facilitated through TL and its incorporated algorithms. Using ethnographic data from five UK clinical sites, we argue that knowledge generated through TL is contingent upon complex human-machine interactions that produce local uncertainties. Thus, algorithms do not simply add medical knowledge. Rather, they rearrange professional practice and expertise. Firstly, we show how TL changes lab routines and training needs. Secondly, we show that the human input TL requires renders the algorithm itself an uncertain and situated practice. This, in turn, raises professional questions about the algorithm's authority in embryo selection. The article demonstrates the embedded nature of algorithmic knowledge production, thus pointing to the need for STS scholarship to further explore the locality of algorithms and AI.

Keywords

References

  1. Med Law Rev. 2012 Summer;20(3):255-303 [PMID: 22647978]
  2. Sociol Health Illn. 2007 Nov;29(7):1091-106 [PMID: 18092985]
  3. Hum Reprod. 2007 Feb;22(2):548-57 [PMID: 17095516]
  4. Fertil Steril. 2006 Dec;86(6):1608-15 [PMID: 17074349]
  5. Fertil Steril. 1995 Oct;64(4):757-63 [PMID: 7672147]
  6. Int J Med Inform. 1999 Aug;55(2):87-101 [PMID: 10530825]
  7. IEEE Pulse. 2015 May-Jun;6(3):22-7 [PMID: 25974911]
  8. Fertil Steril. 2012 Jun;97(6):1277-86 [PMID: 22480821]
  9. Fertil Steril. 2014 Nov;102(5):1295-1300.e2 [PMID: 25225070]
  10. Mol Aspects Med. 2013 Oct;34(5):903-18 [PMID: 23563243]
  11. Sociol Health Illn. 2019 Oct;41 Suppl 1:193-209 [PMID: 31599989]
  12. Hum Reprod Open. 2019 Aug 08;2019(3):hoz017 [PMID: 31406934]
  13. Sociol Health Illn. 2003;25:97-114 [PMID: 14498932]
  14. Reprod Biomed Online. 2017 Oct;35(4):391-399 [PMID: 28756898]
  15. Reprod Biomed Online. 2013 Feb;26(2):120-9 [PMID: 23273754]
  16. Sociol Health Illn. 2021 Nov;43(9):2015-2030 [PMID: 34564881]
  17. Hum Reprod Update. 2014 Sep-Oct;20(5):617-31 [PMID: 24890606]
  18. Soc Sci Med. 2006 Jul;63(1):189-99 [PMID: 16455171]
  19. Soc Sci Med. 2020 Aug;258:113115 [PMID: 32593117]
  20. Reprod Biomed Online. 2013 Nov;27(5):539-46 [PMID: 23933036]
  21. Soc Sci Med. 2006 May;62(10):2349-59 [PMID: 16289740]
  22. Gynecol Obstet Fertil. 2012 Sep;40(9):476-80 [PMID: 22901784]
  23. Sociol Health Illn. 2007 Mar;29(2):180-97 [PMID: 17381812]
  24. Ups J Med Sci. 2020 May;125(2):77-84 [PMID: 32096675]
  25. Fertil Steril. 2012 Dec;98(6):1458-63 [PMID: 22925687]

Grants

  1. /Wellcome Trust

Word Cloud

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