Therapeutic Application, Phytoactives and Pharmacology of Tinospora cordifolia: An Evocative Review.

Rabiya Ahsan, Anuradha Mishra, Badruddeen Badar, Mohammad Owais, Vijayshwari Mishra
Author Information
  1. Rabiya Ahsan: Research Scholar, Faculty of Pharmacy, Integral University, Lucknow, UP, 226022, India.
  2. Anuradha Mishra: Department of Pharmacology, Amity Institute of Pharmacy, Lucknow, Amity University Uttar Pradesh, Sector 125, Noida, 201313, India. misra.anuradha@gmail.com.
  3. Badruddeen Badar: Research Scholar, Faculty of Pharmacy, Integral University, Lucknow, UP, 226022, India.
  4. Mohammad Owais: Research Scholar, Faculty of Pharmacy, Integral University, Lucknow, UP, 226022, India.
  5. Vijayshwari Mishra: Research Scholar, Rameshwaram Institute of Technology, Lucknow, India.

Abstract

Tinospora cordifolia (Guduchi or Gurjo), a herbaceous vine or climbing deciduous shrub, is consider as an important medicine in the Ayurvedic system of medication, which is available in India, China, Myanmar, Bangladesh and Srilanka. Menispermaceae is the family of this compound. T. cordifolia have a variety of properties to treat various ailments such as fevers, jaundice, diabetes, dysentery, urinary infections, and skin diseases. This compound has been subjected to many chemicals, pharmacological, pre-clinical, or clinical investigations and some new therapeutic potential effects have been indicated. This review aims to summarize the critical information concerning in areas of chemical constituents, chemical structure, and pharmacokinetic activities such as anti-diabetic, anticancer, immune-modulatory, antivirus (especially in silico study about COVID-19), antioxidant, antimicrobial, hepatoprotective and its effect on cardiovascular and neurological disorders as well as rheumatoid arthritis. This traditional herb needs more experimental study on the clinical, pre-clinical study, and clinical efficacy of these compounds for the prevention and treatment of COVID-19 and needs large-scale clinical studies to prove the clinical efficacy of this compound, especially in stress-related diseases and other neuronal disorders.

Keywords

References

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MeSH Term

Humans
Tinospora
COVID-19
Plant Extracts
Antioxidants

Chemicals

guduchi
Plant Extracts
Antioxidants

Word Cloud

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