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BMC psychology
Sep 01, 2023;11 (1): 259.

Health-related quality of life and its related factors in patients with systemic lupus erythematosus in southwest Iran: a cross-sectional study.

Sakineh Hashemi, Sahar Farahbakhsh, Zahra Aghakhani, Ali MomayezanMarnani, Nazi Hemati, Somayeh Hashemi
Author Information
  1. Sakineh Hashemi: Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  2. Sahar Farahbakhsh: Occupational Therapy, Zanjan University of Medical Sciences, Zanjan, Iran.
  3. Zahra Aghakhani: Science, York University, Toronto, Canada.
  4. Ali MomayezanMarnani: Nursing, Isfahan University of Medical Sciences, Isfahan, Iran.
  5. Nazi Hemati: Clinical Exercise Physiology, Shiraz University, Shiraz, Iran.
  6. Somayeh Hashemi: Clinical Exercise Physiology, Shiraz University, Shiraz, Iran. Saha_ha33@yahoo.com.
PMID: 37658385 DOI: 10.1186/s40359-023-01300-5

Abstract

BACKGROUND: Quality of life (QoL) is an important measure in health assessment. It is impacted by unclear factors in Systemic Lupus Erythematosus (SLE) patients. The study aimed to investigate the factors related to QoL in SLE patients.
METHODS: This cross-sectional study was performed on 140 (136 women and four men) Iranian SLE patients of Hafiz Hospital from June 2019 to August 2020. The Lupus Erythematosus Quality of Life Questionnaire (LEQoL) was used to evaluate the quality of life. The patients were evaluated with this questionnaire for four weeks in eight dimensions health, emotional health, body image, pain, planning, intimate relationships, and the burden of others. Related factors of LEQoL were evaluated using multivariable linear regression.
RESULTS: The mean age was 34.09(8.96) years. The total mean QoL Score was 65.5 ± 22.4. The multivariable analysis showed that duration of disease (β:-1.12, 95% CI:-1.44 to -0.79, P:0.001), physical activity(β:-12.99, 95% CI:-19.2 to -6.13, P:0.001), kidney involvement (β:-9.2, 95% CI:-16.61 to -2.79, P:0.03) and skin involvement(β:-8.7, 95% CI:-17.2 to -0.2, P:0.031) were significantly related to the total mean QOL score of SLE patients.
CONCLUSION: The QoL of Iranian patients with SLE was low. Age and gender can be related to the decrease in the QoL of patients with SLE. Increasing the disease duration, physical activity, kidney involvement, and skin involvement can be related to the decrease in the QOL of Iranian patients with SLE.

Keywords

Iranian people Quality of life Systemic Lupus Erythematosus

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MeSH Term

Male
Humans
Female
Adult
Cross-Sectional Studies
Quality of Life
Iran
Body Image
Lupus Erythematosus, Systemic
Journal Article

Word Cloud

Created with Highcharts 10.0.0patientsSLEQoLrelatedlifefactorsIranian95%P:02involvementQualityhealthLupusErythematosusstudymeanSystemiccross-sectionalfourLEQoLqualityevaluatedmultivariabletotaldurationdisease-079001physicalactivitykidneyskinQOLcandecreaseBACKGROUND:importantmeasureassessmentimpactedunclearaimedinvestigateMETHODS:performed140136womenmenHafizHospitalJune2019August2020LifeQuestionnaireusedevaluatequestionnaireweekseightdimensionsemotionalbodyimagepainplanningintimaterelationshipsburdenothersRelatedusinglinearregressionRESULTS:age3409896yearsScore655 ± 224analysisshowedβ:-112CI:-144β:-1299CI:-19-613β:-9CI:-1661-203β:-87CI:-17031significantlyscoreCONCLUSION:lowAgegenderIncreasingHealth-relatedsystemiclupuserythematosussouthwestIran:people

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