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03 04, 2024;14 (1): 5234.

A case-control study on health-related quality of life of systemic lupus erythematosus patients.

Rania H Refai, Mohammed F Hussein, Mamdouh H Abdou, Anna N Abou-Raya
Author Information
  1. Rania H Refai: Department of Medicine Supply and Pharmacy, Alexandria University Hospitals, Alexandria University, Alexandria, Egypt. hiph.rattia@alexu.edu.eg. ORCID
  2. Mohammed F Hussein: High Institute of Public Health, Alexandria University, Alexandria, Egypt. ORCID
  3. Mamdouh H Abdou: High Institute of Public Health, Alexandria University, Alexandria, Egypt.
  4. Anna N Abou-Raya: Faculty of Medicine, Alexandria University, Alexandria, Egypt.
PMID: 38433285 DOI: 10.1038/s41598-024-55833-9

Abstract

Systemic lupus erythematosus (SLE) is a chronic rheumatic autoimmune condition that can cause a wide range of symptoms and problems that may affect the health-related quality of life. The main objective of the study was to assess the SLE burden by exploring the effect of the disease on health-related quality of life. The study consisted of 29 female SLE patients and 27 healthy female controls; they were matched for age and parity. A 36-item Short Form health survey questionnaire (SF-36) was used to collect data from participants through face-to-face interviews and to assess their health-related quality of life. SF-36 summary scores for the physical and mental components were decreased in the studied patients compared with controls; PCS was 28.81 ± 16.63, 77.25 ± 15.75 for cases and controls, respectively; and MCS was 32.75 ± 18.69, and 78.75 ± 10.63 for cases and controls, respectively (p < 0.05). The high correlation between the two dimensions characterizes this decrease. SLE negatively affected the quality of life of the patients. Measures such as lifestyle modifications, physical activity, and a healthy diet should be taken to improve the health-related quality of life in SLE patients. In addition, raising the patient's awareness about the disease and its consequences could help to cope with the illness and engage in social and physical activities.

Keywords

Health-related quality of life SF-36 SLE SLE burden

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MeSH Term

Pregnancy
Humans
Female
Quality of Life
Case-Control Studies
Life Style
Behavior Therapy
Lupus Erythematosus, Systemic
Rheumatic Diseases
Journal Article

Word Cloud

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