Weighing the role of social cognition and executive functioning in pragmatics in the schizophrenia spectrum: A systematic review and meta-analysis.

Federico Frau, Chiara Cerami, Alessandra Dodich, Marta Bosia, Valentina Bambini
Author Information
  1. Federico Frau: Laboratory of Neurolinguistics and Experimental Pragmatics (NEP), Department of Humanities and Life Sciences, University School for Advanced Studies IUSS, Pavia, Italy. Electronic address: federico.frau@iusspavia.it.
  2. Chiara Cerami: IUSS Cognitive Neuroscience (ICoN) Center, University School for Advanced Studies IUSS, Pavia, Italy; Dementia Research Center, IRCCS Mondino Foundation, Pavia, Italy.
  3. Alessandra Dodich: Center for Mind/Brain Sciences-CIMeC, University of Trento, Rovereto, Italy.
  4. Marta Bosia: School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Schizophrenia Research and Clinical Unit, IRCCS San Raffaele Hospital, Milan, Italy.
  5. Valentina Bambini: Laboratory of Neurolinguistics and Experimental Pragmatics (NEP), Department of Humanities and Life Sciences, University School for Advanced Studies IUSS, Pavia, Italy.

Abstract

Pragmatic impairment is diffused in schizophrenia spectrum disorders, but the literature still debates its neurocognitive underpinnings. This systematic review and meta-analysis aimed to investigate the neurocognitive correlates of pragmatic disorders in schizophrenia and determine the weight of social cognition and executive functioning on such disorders. Of the 2,668 records retrieved from the literature, 16 papers were included in the systematic review, mostly focused on non-literal meanings and discourse production in schizophrenia. Ten studies were included in the meta-analysis: pragmatics was moderately associated with both social cognition and executive functions (especially inhibition), but the link with social cognition was stronger. The mediation analysis showed that social cognition mediated the relationship between executive functions and pragmatics. Based on this, we proposed a hierarchical neurocognitive model where pragmatics stems from social cognition, while executive functions are the fertile ground supporting the other two domains, and we discuss its theoretical and clinical implications.

Keywords

MeSH Term

Humans
Executive Function
Social Cognition
Schizophrenia
Schizophrenic Psychology

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