Trauma exposure across the lifespan among individuals engaged in treatment with medication for opioid use disorder: differences by gender, PTSD status, and chronic pain.

Monique N Rodr��guez, Dana D Colgan, Sarah Leyde, Kenneth Pike, Joseph O Merrill, Cynthia J Price
Author Information
  1. Monique N Rodr��guez: Department of Individual, Family, and Community Education, University of New Mexico USA, Simpson Hall MSC053042, 502 Campus, Blvd, Albuquerque, NM, 87131, USA.
  2. Dana D Colgan: Department of Neurology, Oregon Health and Science University USA, 3818 SW Sam Jackson Parkway, Portland, OR, 97229, USA.
  3. Sarah Leyde: School of Medicine, University of Washington, Seattle, WA, 98104, USA.
  4. Kenneth Pike: Department of Child Family and Population Health Nursing, University of Washington USA, Seattle, USA.
  5. Joseph O Merrill: School of Medicine, University of Washington, Seattle, WA, 98104, USA.
  6. Cynthia J Price: Department of Biobehavioral Nursing and Health Informatics, University of WA, Seattle, USA. cynthiap@uw.edu.

Abstract

BACKGROUND: There is little study of lifetime trauma exposure among individuals engaged in medication treatment for opioid use disorder (MOUD). A multisite study provided the opportunity to examine the prevalence of lifetime trauma and differences by gender, PTSD status, and chronic pain.
METHODS: A cross-sectional study examined baseline data from participants (N���=���303) enrolled in a randomized controlled trial of a mind-body intervention as an adjunct to MOUD. All participants were stabilized on MOUD. Measures included the Trauma Life Events Questionnaire (TLEQ), the Brief Pain Inventory (BPI), and the Posttraumatic Stress Disorder Checklist (PCL-5). Analyses involved descriptive statistics, independent sample t-tests, and linear and logistic regression.
RESULTS: Participants were self-identified as women (n���=���157), men (n���=���144), and non-binary (n���=���2). Fifty-seven percent (n���=���172) self-reported chronic pain, and 41% (n���=���124) scored above the screening cut-off for PTSD. women reported significantly more intimate partner violence (85%) vs 73%) and adult sexual assault (57% vs 13%), while men reported more physical assault (81% vs 61%) and witnessing trauma (66% vs 48%). men and women experienced substantial childhood physical abuse, witnessed intimate partner violence as children, and reported an equivalent exposure to accidents as adults. The number of traumatic events predicted PTSD symptom severity and PTSD diagnostic status. Participants with chronic pain, compared to those without chronic pain, had significantly more traumatic events in childhood (85% vs 75%).
CONCLUSION: The study found a high prevalence of lifetime trauma among people in MOUD. Results highlight the need for comprehensive assessment and mental health services to address trauma among those in MOUD treatment.
TRIAL REGISTRATION: NCT04082637.

Keywords

Associated Data

ClinicalTrials.gov | NCT04082637

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Grants

  1. R01 AT010742/NCCIH NIH HHS
  2. R01 DA033324/NIDA NIH HHS
  3. R33 AT009932/NCCIH NIH HHS

MeSH Term

Humans
Stress Disorders, Post-Traumatic
Chronic Pain
Female
Male
Cross-Sectional Studies
Adult
Opioid-Related Disorders
Sex Factors
Middle Aged
Psychological Trauma

Word Cloud

Created with Highcharts 10.0.0paintraumaMOUDPTSDchronicvsstudyamonglifetimeexposureusedisorderdifferencesstatusTraumareportedtreatmentindividualsengagedmedicationopioidprevalencegenderparticipantsParticipantswomenmensignificantlyintimatepartnerviolence85%assaultphysicalchildhoodtraumaticeventsBACKGROUND:is littletreatment for AmultisiteprovidedopportunityexamineMETHODS:cross-sectionalexaminedbaselinedataN���=���303enrolledrandomizedcontrolledtrialmind-bodyinterventionadjunctstabilizedMeasuresincludedLifeEventsQuestionnaireTLEQBriefPainInventoryBPIPosttraumaticStressDisorderChecklistPCL-5Analysesinvolveddescriptivestatisticsindependentsamplet-testslinearlogisticregressionRESULTS:self-identifiedn���=���157n���=���144non-binaryn���=���2Fifty-sevenpercentn���=���172self-reported41%n���=���124scoredscreeningcut-offWomen73%adultsexual57%13%81%61%witnessing66%48%Menexperiencedsubstantialabusewitnessedchildrenequivalentaccidentsadultsnumberpredictedsymptomseveritydiagnosticcomparedwithout75%CONCLUSION:foundhighpeopleResultshighlightneedcomprehensiveassessmentmentalhealthservicesaddressTRIALREGISTRATION:NCT04082637acrosslifespandisorder:ChronicGenderMedicationOpioidPost-traumaticstress

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