Practice-based research in dentistry: Exploring methodologies, benefits, and challenges.

Rahma Mungia, Ellen Funkhouser, Frank Lobbezoo, Merel Charlotte Verhoeff, Gregg H Gilbert, National Dental PBRN Collaborative Group
Author Information
  1. Rahma Mungia: Department of Periodontics, School of Dentistry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. ORCID
  2. Ellen Funkhouser: Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  3. Frank Lobbezoo: Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. ORCID
  4. Merel Charlotte Verhoeff: Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. ORCID
  5. Gregg H Gilbert: Department of Clinical and Community Sciences, School of Dentistry, National Network Director, National Dental PBRN, University of Alabama at Birmingham, Birmingham, Alabama, USA. ORCID

Abstract

BACKGROUND: Practice-Based Research Network (PBRN) studies typically assess the effectiveness of clinical interventions in settings that match real-world conditions. Dental PBRNs have the capacity to amass, identify, and analyze vast amounts of data from patient populations that include diverse racial, ethnic, socio-economic, and geographic backgrounds. These dental studies encompass a broad spectrum of healthcare aspects, including prevention, diagnosis, symptom and disease treatment, quality enhancement, and care coordination.
METHODS: An extensive range of research methodologies can be employed within dental PBRNs to investigate these topics, including randomized controlled trials. Dental PBRNs have evolved from primarily focusing on case observations to leveraging advanced network infrastructure and collaborating across multiple regional and national sites. In addition to producing numerous high-impact peer-reviewed publications, study results have led to improved clinical care. However, PBRNs encounter challenges, such as the sustainability of research capacity (relying heavily on ongoing support from funding agencies), diverse research cultures, and an imperative to design studies that are both feasible and relevant to everyday clinical practice. Recognizing the pivotal role of real-world evidence, it is important to have sustained investment in dental PBRN infrastructure and feasible opportunities for practitioners to participate in network activities nationwide.
CONCLUSION: Practice-Based Research Network studies capitalize on an important research context within which to investigate a range of clinical topics that can employ multiple research methodologies. However, sustaining productive networks requires strategic effort, ongoing financial support, and customized organizational skills.

Keywords

References

  1. J Am Dent Assoc. 2017 Oct;148(10):728-736 [PMID: 28629602]
  2. J Am Dent Assoc. 2016 Nov;147(11):882-890 [PMID: 27492046]
  3. J Healthc Leadersh. 2012 Sep;4:107-116 [PMID: 26213481]
  4. Braz Oral Res. 2020;34 Suppl 2:e071 [PMID: 32785489]
  5. Acad Med. 2010 Mar;85(3):476-83 [PMID: 20182121]
  6. J Am Dent Assoc. 2018 Apr;149(4):299-307.e1 [PMID: 29475554]
  7. J Am Dent Assoc. 2021 Feb;152(2):146-156 [PMID: 33358237]
  8. J Vet Intern Med. 2019 Mar;33(2):356-362 [PMID: 30784125]
  9. BMC Oral Health. 2014 Jun 05;14:64 [PMID: 24902842]
  10. J Clin Transl Sci. 2022 Jun 22;6(1):e87 [PMID: 35989860]
  11. J Dent. 2013 Nov;41(11):1051-9 [PMID: 23597500]
  12. J Am Board Fam Med. 2018 Nov-Dec;31(6):844-856 [PMID: 30413541]
  13. J Dent. 2021 Jan;104:103523 [PMID: 33186627]
  14. J Dent Res. 2015 Oct;94(10):1355-61 [PMID: 26318590]
  15. J Am Dent Assoc. 2018 May;149(5):353-362 [PMID: 29550022]
  16. J Am Board Fam Med. 2020 Sep-Oct;33(5):687-697 [PMID: 32989063]
  17. Cranio. 2023 Apr 4;:1-9 [PMID: 37016587]
  18. Implement Sci. 2014 Dec 02;9:177 [PMID: 25603497]
  19. Community Dent Oral Epidemiol. 2013 Apr;41(2):143-53 [PMID: 23036131]
  20. J Dent. 2018 Mar;70:67-73 [PMID: 29289728]
  21. Health Promot Pract. 2021 Jan;22(1):18-20 [PMID: 32281882]
  22. J Can Dent Assoc. 2010;76:a93 [PMID: 20831853]
  23. J Public Health Dent. 2014 Fall;74(4):276-82 [PMID: 24707895]
  24. J Am Dent Assoc. 2023 Mar;154(3):235-244 [PMID: 36690539]
  25. J Am Dent Assoc. 2012 Apr;143(4):377-85 [PMID: 22467698]
  26. Prog Community Health Partnersh. 2015 Autumn;9(3):447-56 [PMID: 26548797]
  27. Tex Dent J. 2022 Sep;139(9):542-554 [PMID: 36644550]
  28. J Dent Res. 2022 Sep;101(10):1133-1134 [PMID: 35331053]
  29. Lancet. 2019 Jul 20;394(10194):249-260 [PMID: 31327369]
  30. Caries Res. 2008;42(3):164-70 [PMID: 18446024]

Grants

  1. UM1-TR-004538/NIH HHS
  2. U19-DE-28717/NIH HHS
  3. U19-DE-22516/NIH HHS
  4. UM1 TR004538/NCATS NIH HHS
  5. U01 DE028727/NIDCR NIH HHS
  6. /NIH HHS
  7. U19 DE028717/NIDCR NIH HHS

Word Cloud

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