Hodgkin's Lymphoma after Initiation of Antiretroviral Therapy in a Patient from India.

Vinay Kumar Konan, S T Kavya, Mohan C Nagchand, Bhushan C Shetty
Author Information
  1. Vinay Kumar Konan: Junior Resident, Department of Medicine, BMCRI, RGUHS, Bengaluru, India.
  2. S T Kavya: Professor, Department of Medicine, BMCRI, RGUHS, Bengaluru, India.
  3. Mohan C Nagchand: Assistant Professor, Department of Medicine, SABVMRI, RGUHS, Bengaluru, India.
  4. Bhushan C Shetty: Assistant Professor, Department of Nephrology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Abstract

SUMMARY: Malignancies in human immunodeficiency virus (HIV) positive individuals have a larger role in morbidity and mortality. Appropriate clinical acumen is required for a clinician to anticipate the occurrence of lymphoma after starting antiretroviral therapy, especially in patients with CD4 <100 cells/mm3. Here is a 30-year-old man with weight loss and appetite, found to be retroviral disease positive status with low CD 4 counts. He was started on antiretroviral treatment, and following that, he developed Hodgkin's lymphoma of mixed cellularity. He is planned for an ABVD regimen and received one cycle of the same without any complications. To our knowledge, we are reporting the first case of an HIV patient with a mixed cellularity form of classical Hodgkin's lymphoma from India.

References

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  3. Herida M, Mary-Krause M, Kaphan R, Cadranel J, Poizot-Martin I, Rabaud C, et al. Incidence of non-AIDS-defining cancers before and during the highly active antiretroviral therapy era in a cohort of human immunodeficiency virus-infected patients. J Clin Oncol 2003;21:3447–53.
  4. Goedert JJ, Coté TR, Virgo P, Scoppa SM, Kingma DW, Gail MH, et al. Spectrum of AIDS-associated malignant disorders. Lancet 1998;351:1833–9.
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MeSH Term

Humans
Hodgkin Disease
Male
Adult
HIV Infections
India
Antineoplastic Combined Chemotherapy Protocols
CD4 Lymphocyte Count
Doxorubicin
Bleomycin
Dacarbazine
Vinblastine
Anti-Retroviral Agents

Chemicals

Doxorubicin
Bleomycin
Dacarbazine
Vinblastine
Anti-Retroviral Agents

Word Cloud

Created with Highcharts 10.0.0lymphomaHodgkin'sHIVpositiveantiretroviralmixedcellularityIndiaSUMMARY:MalignancieshumanimmunodeficiencyvirusindividualslargerrolemorbiditymortalityAppropriateclinicalacumenrequiredcliniciananticipateoccurrencestartingtherapyespeciallypatientsCD4<100cells/mm330-year-oldmanweightlossappetitefoundretroviraldiseasestatuslowCD4countsstartedtreatmentfollowingdevelopedplannedABVDregimenreceivedonecyclewithoutcomplicationsknowledgereportingfirstcasepatientformclassicalLymphomaInitiationAntiretroviralTherapyPatient

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