Lale Din�� Asarc��kl��: Department of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey. ORCID
Duygu ��nan: Department of Cardiology, Basaksehir Cam & Sakura City Hospital, Istanbul, Turkey. ORCID
Selda Murat: Department of Internal Medical Sciences, Division of Cardiology, Osmangazi University, Eskisehir, Turkey.
��nci Tu����e ����ll��o��lu: Department of Internal Medical Sciences, Division of Cardiology, Karabuk University School of Medicine, Karabuk, Turkey. ORCID
Nijat Bakhshaliyev: Department of Internal Medical Sciences, Division of Cardiology, Bezmialem University School of Medicine, Istanbul, Turkey.
Zeynep Uluta��: Department of Internal Medical Sciences, Division of Cardiology, Inonu University School of Medicine, Malatya, Turkey. ORCID
Gizem ��abuk: Department of Cardiology, Tepecik Research and Training Hospital, Izmir, Turkey.
Senem Has��rc��: Division of Internal Medical Sciences, Department of Cardiology, Baskent University School of Medicine, Ankara, Turkey.
Abdulrahman Naser: Department of Cardiology, K��rklareli Research and Training Hospital, K��rklareli, Turkey.
��ennur ��nal Day��: Department of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.
Ahmet ��elik: Division of Internal Medical Sciences, Department of Cardiology, Mersin University School of Medicine, Mersin, Turkey.
Tolga Sinan G��ven��: Division of Internal Medical Sciences, Department of Cardiology, Istinye University School of Medicine, Istanbul, Turkey. ORCID
BACKGROUND: Echocardiographic right ventricular (RV) dysfunction is a strong risk determinant for prognosis in patients with heart failure (HF). Although parameters of RV systolic function are widely used to define RV dysfunction, there is scarce data to suggest these parameters are best suited to predict HF-related outcomes. AIMS: We aimed to understand which morphologic or functional parameters are most closely associated with short-term mortality and HF-related hospitalization in patients with HF. METHODS: A total of 191 patients from eight study centers were included to this study. A detailed echocardiographic examination was done at enrollment, and patients were followed up for 6 months via direct interviews or phone calls. RESULTS: All right-sided echocardiographic parameters other than tricuspid annular plane systolic excursion were associated with outcomes. In a proportional hazards model that included right-heart parameters, RV longitudinal diameter (HR: 1.07, 95%CI: 1.04-1.10, p < 0.001), wall thickness (HR: 1.3, 95%CI: 1.13-1.50, p < 0.001), and tricuspid annular systolic velocity (HR: 0.90, 95%CI: 0.82-0.96, p = 0.02) were found as the independent predictors. However, only RV longitudinal dimension (HR: 1.04, 95%CI: 1.01-1.08, p = 0.01) and RV wall thickness (HR: 1.32, 95%CI: 1.10-1.60, p = 0.004) were associated with short-term outcomes after adjusting for other clinical and left-sided echocardiographic variables. On a Bayesian logistic regression model that included right-sided echocardiography variables, there was strong evidence for including either RV longitudinal diameter (BF: 190.4) or wall thickness (BF: 30.7) to the final model. CONCLUSION: Parameters of RV morphology were better predictors of short-term outcomes in HF patients.
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