Moral Intuition Regarding the Possibility of Conscious Human Brain Organoids: An Experimental Ethics Study.

Koji Ota, Tetsushi Tanibe, Takumi Watanabe, Kazuki Iijima, Mineki Oguchi
Author Information
  1. Koji Ota: Institute of Humanities and Social Sciences, University of Tsukuba, Tsukuba, Japan. ota.koji.fw@u.tsukuba.ac.jp. ORCID
  2. Tetsushi Tanibe: School of Culture, Media and Society, Waseda University, Tokyo, Japan. ORCID
  3. Takumi Watanabe: Institutional Research Center, Hokkaido University of Education, Sapporo, Japan. ORCID
  4. Kazuki Iijima: Brain Science Institute, Tamagawa University, Machida, Japan. ORCID
  5. Mineki Oguchi: Brain Science Institute, Tamagawa University, Machida, Japan. ORCID

Abstract

The moral status of human brain organoids (HBOs) has been debated in view of the future possibility that they may acquire phenomenal consciousness. This study empirically investigates the moral sensitivity in people's intuitive judgments about actions toward conscious HBOs. The results showed that the presence/absence of pain experience in HBOs affected the judgment about the moral permissibility of actions such as creating and destroying the HBOs; however, the presence/absence of visual experience in HBOs also affected the judgment. These findings suggest that people's intuitive judgments about the moral status of HBOs are sensitive to the valence-independent value of phenomenal consciousness. We discuss how these observations can have normative implications; particularly, we argue that they put pressure on the theoretical view that the moral status of conscious HBOs is grounded solely in the valence-dependent value of consciousness. We also discuss how our findings can be informative even when such a theoretical view is finally justified or when the future possibility of conscious HBOs is implausible.

Keywords

References

  1. Front Cell Neurosci. 2020 Aug 28;14:233 [PMID: 33005129]
  2. Behav Brain Sci. 2010 Jun;33(2-3):61-83; discussion 83-135 [PMID: 20550733]
  3. Cell Stem Cell. 2021 Oct 7;28(10):1740-1757.e8 [PMID: 34407456]
  4. EMBO Rep. 2024 Jan;25(1):13-16 [PMID: 38177904]
  5. Stem Cell Reports. 2021 Aug 10;16(8):1874-1883 [PMID: 34329595]
  6. Regen Med. 2020 Dec;15(12):2351-2360 [PMID: 33471559]
  7. Stem Cell Reports. 2019 Sep 10;13(3):440-447 [PMID: 31509736]
  8. Nature. 2017 May 4;545(7652):48-53 [PMID: 28445462]
  9. Bioethics. 2021 Sep;35(7):652-663 [PMID: 33945162]
  10. AJOB Neurosci. 2022 Apr-Jun;13(2):81-94 [PMID: 33769221]
  11. Stem Cell Reports. 2023 Apr 11;18(4):841-852 [PMID: 37001517]
  12. Theor Med Bioeth. 2021 Aug;42(3-4):91-111 [PMID: 34787789]
  13. Neuron. 2022 Dec 7;110(23):3952-3969.e8 [PMID: 36228614]
  14. J Cyst Fibros. 2018 May;17(3):407-415 [PMID: 29523474]
  15. Science. 2005 Oct 7;310(5745):116-9 [PMID: 16210542]
  16. J Law Med Ethics. 2019 Dec;47(4):760-767 [PMID: 31957593]
  17. J Med Ethics. 2018 Sep;44(9):611-612 [PMID: 29535181]
  18. Philos Stud. 2013 Jan;162(2):421-445 [PMID: 23316090]
  19. Cell Stem Cell. 2019 Oct 3;25(4):462-472 [PMID: 31585092]
  20. Monash Bioeth Rev. 2020 Dec;38(2):105-128 [PMID: 32895775]
  21. J Med Ethics. 2018 Sep;44(9):606-610 [PMID: 29491041]
  22. Annu Rev Psychol. 2012;63:81-99 [PMID: 21801019]
  23. Stem Cell Res Ther. 2023 Apr 1;14(1):59 [PMID: 37005693]

Grants

  1. JPMJRX21J7/JST RISTEX
  2. JPMJRS22J4/JST RISTEX
  3. KAKENHI 20H01752/JSPS

MeSH Term

Humans
Consciousness
Intuition
Brain
Organoids
Judgment
Morals
Moral Status
Male
Female
Adult
Ethics, Research
Young Adult
Pain

Word Cloud

Created with Highcharts 10.0.0HBOsmoralstatusconsciousnessviewconsciousbrainorganoidsfuturepossibilityphenomenalpeople'sintuitivejudgmentsactionspresence/absenceexperienceaffectedjudgmentalsofindingsvaluediscusscantheoreticalMoralHumanExperimentalhumandebatedmayacquirestudyempiricallyinvestigatessensitivitytowardThe resultsshowedpainpermissibilitycreatingdestroyinghowevervisualsuggestsensitivevalence-independentobservationsnormativeimplicationsparticularlyargueputpressuregroundedsolelyvalence-dependentinformativeevenfinallyjustifiedimplausibleIntuitionRegardingPossibilityConsciousBrainOrganoids:EthicsStudyethicsPhenomenal

Similar Articles

Cited By