One-Stop Diagnosis in Interventional Pathology: A 7-Year Experience With On-Demand Care for Superficial Nodules.

Karen Villar-Zarra, Héctor Enrique Torres-Rivas, Nerea Guerrero-Fretes, María Del Mar Olmo-Fernández, Raúl Castañeda Vozmediano, Santiago Nieto Llanos, Jesús Nieves-Alonso
Author Information
  1. Karen Villar-Zarra: Pathology Department, Hospital Universitario del Henares, Madrid, Spain. ORCID
  2. Héctor Enrique Torres-Rivas: Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain. ORCID
  3. Nerea Guerrero-Fretes: Pathology Department, Hospital Universitario del Henares, Madrid, Spain.
  4. María Del Mar Olmo-Fernández: Pathology Department, Hospital Universitario del Henares, Madrid, Spain. ORCID
  5. Raúl Castañeda Vozmediano: Department of Support for Research, Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain. ORCID
  6. Santiago Nieto Llanos: Pathology Department, Hospital Universitario del Henares, Madrid, Spain.
  7. Jesús Nieves-Alonso: Department of Anesthesiology and Surgical Critical Care, Hospital Universitario de La Princesa, Madrid, Spain. ORCID

Abstract

BACKGROUND: The growing demand for specialised healthcare often results in prolonged waiting times for diagnostic procedures, particularly in oncological pathology. Interventional pathology, wherein pathologists perform sample collection and diagnosis, offers a potential solution through same-day diagnostic services.
OBJECTIVES: This study aims to describe the operational framework of a One-Stop interventional pathology consultation and analyse its outcomes, focusing on response times and diagnostic performance for patients with superficial nodules.
METHODS: This retrospective study was conducted in a tertiary hospital from 2016 to 2023. The consultation involved ultrasound-guided fine needle aspiration (USFNA) and core needle biopsy (USCNB) performed by an interventional pathologist. Data on procedure adequacy, response times, and diagnostic outcomes were collected and analysed.
RESULTS: A total of 877 procedures (718 USFNA, 159 USCNB) were performed. The median time from specialist request to definitive diagnosis was 2 days (interquartile range 1-4), with 18% of patients receiving a diagnosis on the same day. Adequacy rates were 98.6% for USFNA and 100% for USCNB, with low non-diagnostic rates (USFNA: 3.2%; USCNB: 0.6%). Lymph nodes were the most commonly sampled organ, and head-and-neck areas were the predominant anatomical sites.
CONCLUSIONS: The One-Stop interventional pathology model significantly reduced diagnostic times and improved patient experience. This efficient, patient-centred approach demonstrates high diagnostic accuracy and low non-diagnostic rates, supporting its viability for broader adoption. Further multicentre studies are needed to validate findings and optimise implementation.

Keywords

References

  1. A. Reichert and R. Jacobs, “The Impact of Waiting Time on Patient Outcomes: Evidence From Early Intervention in Psychosis Services in England,” Health Economics 27, no. 11 (2018): 1772–1787.
  2. K. Villar Zarra and S. Nieto Llanos, “Una Nueva Figura en la Anatomía Patológica Actual: el Patólogo Intervencionista,” Revista Española de Patología 49, no. 2 (2016): 94–95.
  3. K. Villar Zarra, H. E. Torres Rivas, S. D. Rollins, L. M. Fernández Fernández, and S. Nieto Llanos, “Systematized Protocol for Interventional Pathology Reports. Pathology Report Paradigm for Pathologist‐Performed Ultrasound Guided Fine Needle Aspiration (USFNA) and Ultrasound Guided Core Needle Biopsy (USCNB),” Revista Española de Patología 52, no. 3 (2019): 163–166.
  4. M. F. Valdivia‐Mazeyra, C. Salas, J. M. Nieves‐Alonso, et al., “Increased Number of Pulmonary Megakaryocytes in COVID‐19 Patients With Diffuse Alveolar Damage: An Autopsy Study With Clinical Correlation and Review of the Literature,” Virchows Archiv 478, no. 3 (2021): 487–496.
  5. M. Del Mar Olmo Fernandez, L. Wheeldon, and K. Villar‐Zarra, “Key Roles of the Cytotechnologists and Biomedical Scientists in Interventional Pathology: The Foundation of a Seamless Workflow,” Cytopathology, ahead of print, March 22, 2024, https://doi.org/10.1111/cyt.13375.
  6. K. Villar‐Zarra, J. Nieves‐Alonso, and H. Torres‐Rivas, “Antithrombotic Therapy—A Simple Algorithm for the Interventional Pathologist: A Case Series,” Cytopathology, ahead of print, March 25, 2024, https://doi.org/10.1111/cyt.13377.
  7. T. J. Lynn and S. E. Monaco, “Adding the “US” in FNA: Pearls for Starting a Pathologist‐Performed Ultrasound‐Guided Fine Needle Aspiration Service (USG FNA),” Seminars in Diagnostic Pathology 39, no. 6 (2022): 410–420.
  8. B. H. Matt, H. K. Woodward‐Hagg, C. L. Wade, P. D. Butler, and M. S. Kokoska, “Lean Six Sigma Applied to Ultrasound Guided Needle Biopsy in the Head and Neck,” Otolaryngology–Head and Neck Surgery 151, no. 1 (2014): 65–72.
  9. D. Lieu, “Cytopathologist‐Performed Ultrasound‐Guided Fine‐Needle Aspiration and Core‐Needle Biopsy: A Prospective Study of 500 Consecutive Cases,” Diagnostic Cytopathology 36, no. 5 (2008): 317–324.
  10. M. Wu, Y. Choi, Z. Zhang, et al., “Ultrasound Guided FNA of Thyroid Performed by Cytopathologists Enhances Bethesda Diagnostic Value,” Diagnostic Cytopathology 44, no. 10 (2016): 787–791.
  11. D. R. McKenzie, E. G. Kliassov, R. C. Dash, W. Foo, C. K. Jones, and X. Jiang, “Pathologist‐Performed Ultrasound‐Guided Fine‐Needle Aspirations of the Thyroid: A Single Institution Observational Study,” Cancer Cytopathology 130, no. 9 (2022): 735–739.
  12. R. Conrad, S. E. Yang, S. Chang, et al., “Comparison of Cytopathologist‐Performed Ultrasound‐Guided Fine‐Needle Aspiration With Cytopathologist‐Performed Palpation‐Guided Fine‐Needle Aspiration: A Single Institutional Experience,” Archives of Pathology & Laboratory Medicine 142, no. 10 (2018): 1260–1267.
  13. B. T. Collins, B. DuBray‐Benstein, K. Naik, M. A. Smith, and P. G. Tiscornia‐Wasserman, “Commentary: American Society of Cytopathology Rapid on‐Site Evaluation (ROSE) Position Statement,” Journal of the American Society of Cytopathology 4, no. 2 (2015): I.
  14. T. Sood, M. Supriya, J. Thopil, V. Surendra, and B. B. Patel, “One Stop Neck Lump Clinic: A Boon for Quick Diagnosis and Early Management,” European Archives of Oto‐Rhino‐Laryngology 278, no. 12 (2021): 4951–4954.
  15. C. Friedemann Smith, A. Tompson, G. A. Holtman, et al., “General Practitioner Referrals to One‐Stop Clinics for Symptoms That Could Be Indicative of Cancer: A Systematic Review of Use and Clinical Outcomes,” Family Practice 36, no. 3 (2019): 255–261.
  16. V. Suciu, C. El Chamieh, R. Soufan, et al., “Real‐World Diagnostic Accuracy of the on‐Site Cytopathology Advance Report (OSCAR) Procedure Performed in a Multidisciplinary One‐Stop Breast Clinic,” Cancers 15, no. 20 (2023): 4967.
  17. V. Ciliberti, E. Maffei, A. D'Ardia, et al., “Combined Fine Needle Aspiration Cytology and Core Needle Biopsy in the Same Setting: A Two‐years' Experience,” Cytopathology 35, no. 1 (2024): 78–91.

Word Cloud

Created with Highcharts 10.0.0diagnostictimespathologyinterventionaldiagnosisOne-StopUSFNAUSCNBratesproceduresInterventionalservicesstudyconsultationoutcomesresponsepatientsneedlebiopsyperformed6%lownon-diagnosticpatientBACKGROUND:growingdemandspecialisedhealthcareoftenresultsprolongedwaitingparticularlyoncologicalwhereinpathologistsperformsamplecollectionofferspotentialsolutionsame-dayOBJECTIVES:aimsdescribeoperationalframeworkanalysefocusingperformancesuperficialnodulesMETHODS:retrospectiveconductedtertiaryhospital20162023involvedultrasound-guidedfineaspirationcorepathologistDataprocedureadequacycollectedanalysedRESULTS:total877718159mediantimespecialistrequestdefinitive2 daysinterquartilerange1-418%receivingdayAdequacy98100%USFNA:32%USCNB:0Lymphnodescommonlysampledorganhead-and-neckareaspredominantanatomicalsitesCONCLUSIONS:modelsignificantlyreducedimprovedexperienceefficientpatient-centredapproachdemonstrateshighaccuracysupportingviabilitybroaderadoptionmulticentrestudiesneededvalidatefindingsoptimiseimplementationDiagnosisPathology:7-YearExperienceOn-DemandCareSuperficialNodulescytologyfine‐needlecaremanagementpoint‐of‐caretestingultrasonography

Similar Articles

Cited By

No available data.