This study explored the health, gender, and economic benefits of self-employment in China from 2000 to 2021. The findings using descriptive analysis and graphs, indicate a steady improvement in life expectancy, suggesting advancements in healthcare and living conditions, while self-employment participation has fluctuated, revealing its potential as a flexible income source during economic downturns. Despite a decline in employment in formal sector, self-employment appears to contribute to economic resilience, offering alternative employment avenues. Additionally, the study highlights a modest decline in gender inequality alongside decreasing participation in self-employment, indicating a possible shift towards more stable employment structures that promote equity. We conclude that self-employment can enhance health outcomes, support gender equity, and provide economic stability. We recommend continued policy support to sustain its benefits within China's evolving labour landscape.