Ahmedabad declaration: A framework to combat growing epidemic of young-onset type 2 diabetes in Asia.

Rakesh M Parikh, Banshi Saboo, Anoop Misra, Abdul Basit, S R Aravind, Bishwajit Bhowmik, Peter Schwarz, Ketan Dhatariya, Kamlesh Khunti, Shashank Joshi, Sunil Gupta, Amit Gupta, Manoj Chawla, Sanjeev Phatak, Sanjay Kalra, Azad Khan, Viswanathan Mohan, Ahmedabad Declaration Committee Members
Author Information
  1. Rakesh M Parikh: Diabecity Clinic, Jaipur, India; C K S Hospital, Jaipur, India. Electronic address: drrakeshparikh@gmail.com.
  2. Banshi Saboo: Diacare Diabetes Care & Hormone Clinic, Ahmedabad, India.
  3. Anoop Misra: Fortis C-DOC Center of Excellence for Diabetes, Metabolic Diseases and Endocrinology, New Delhi, India; National Diabetes Obesity and Cholesterol Foundation, New Delhi, India; Diabetes Foundation (India), New Delhi, India.
  4. Abdul Basit: Indus Diabetes and Endocrinology Center, Indus Hospital and Health Network, Pakistan; Diabetic Association of Pakistan, Pakistan; Health Promotion Foundation, Pakistan; Diabetes in Asia Study Group, Doha, Qatar; Health Research Advisory Board, Pakistan.
  5. S R Aravind: Diacon Hospital, Bangalore, India; Research Trust of Diabetes India, Ahmedabad, India.
  6. Bishwajit Bhowmik: Centre for Global Health Research, Dhaka, Bangladesh; Diabetic Association of Bangladesh, Dhaka, Bangladesh.
  7. Peter Schwarz: International Diabetes Federation (IDF), Avenue Herrmann-Debroux 54., B-1160, Brussels, Belgium; Department for Prevention and Care of Diabetes, Faculty of Medicine, Carl Gustav Carus at the Technische Universität/TU Dresden, Dresden, Germany; Paul Langerhans Institute Dresden of Helmholtz Zentrum München at University Hospital and Faculty of Medicine, TU Dresden, 01307, Dresden, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, 85764, Germany.
  8. Ketan Dhatariya: Elsie Bertram Diabetes Centre, Norfolk & Norwich University Hospitals NHS Foundation Trust, Norwich, NR4 7UY, UK; Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, UK.
  9. Kamlesh Khunti: Diabetes Research Centre, University of Leicester, Leicester, LE5 4PW, UK; Leicester Real World Evidence Unit, Diabetes Research Centre, University of Leicester, Leicester, LE5 4PW, UK; NIHR ARC East Midlands, University of Leicester, UK.
  10. Shashank Joshi: Department of Diabetology & Endocrinology, Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India.
  11. Sunil Gupta: Sunil's Diabetes Care and Research Centre, Nagpur, India.
  12. Amit Gupta: Centre for Diabetes Care, Greater Noida, Uttar Pradesh, India.
  13. Manoj Chawla: Lina Diabetes Care and Mumbai Diabetes Research Centre, Mumbai, India.
  14. Sanjeev Phatak: Department of Diabetes and Metabolism, MARENGO CIMS Hospital, Ahmedabad, India; VIjayratna Diabetes Centre, Ahmedabad, India; J S Thakershy Hospital, Ahmedabad, India.
  15. Sanjay Kalra: Bharti Hospital, Karnal, Haryana, India; University Centre for Research and Development, Chandigarh University, Mohali, India.
  16. Azad Khan: Centre for Global Health Research, Dhaka, Bangladesh; Diabetic Association of Bangladesh, Dhaka, Bangladesh; Department of Public Health, Bangladesh University of Health Sciences, Dhaka, Bangladesh.
  17. Viswanathan Mohan: Madras Diabetes Research Foundation [ICMR- Collaborating Centre of Excellence (ICMR-CCoE)], India; Dr. Mohan's Diabetes Specialties Centre (IDF Centre of Excellence in Diabetes Care), Chennai, India.

Abstract

AIM: Rising prevalence of Type 2 Diabetes (T2D) among young Asians has emerged as a public health crisis that threatens the long-term health, economic stability, and productivity of nations across Asia (1). Early-onset T2D poses unique challenges, including higher rates of undiagnosed cases, more aggressive disease progression, an increased risk of chronic complications and higher mortality (2). Hyperglycemia during the reproductive age especially among the female population can potentially have transgenerational impact through epigenetic changes.
METHODS: A comprehensive search was conducted on PubMed with a combination of relevant keywords. A preliminary draft prepared after review of literature was electronically circulated among a panel of 64 experts from various parts of the region and representatives of the participating organizations - Diabetes India (www.diabetesindia.org.in) and the Diabetes Asia Study Group (DASG, www.da-sg.org).
RESULTS: This Ahmedabad Declaration outlines the scale of the problem, its root causes, and a comprehensive action plan for Asian populations. The objectives of this declaration include raising awareness, addressing systemic barriers, and advocating for evidence-based policies and interventions, limited to people with T2D. Through collaborative efforts, we aim to mitigate the growing burden of diabetes in young Asians and secure a healthier future.

Keywords

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Grants

  1. K23 MD016230/NIMHD NIH HHS

MeSH Term

Humans
Diabetes Mellitus, Type 2
Asia
Age of Onset
Prevalence
Epidemics
Female
Prognosis

Word Cloud

Created with Highcharts 10.0.0T2DAsia2DiabetesamongAsiansyounghealthhighercomprehensivewwworgAhmedabadAsiangrowingdiabetesAIM:RisingprevalenceTypeemergedpubliccrisisthreatenslong-termeconomicstabilityproductivitynationsacross1Early-onsetposesuniquechallengesincludingratesundiagnosedcasesaggressivediseaseprogressionincreasedriskchroniccomplicationsmortalityHyperglycemiareproductiveageespeciallyfemalepopulationcanpotentiallytransgenerationalimpactepigeneticchangesMETHODS:searchconductedPubMedcombinationrelevantkeywordspreliminarydraftpreparedreviewliteratureelectronicallycirculatedpanel64expertsvariouspartsregionrepresentativesparticipatingorganizations-IndiadiabetesindiainStudyGroupDASGda-sgRESULTS:Declarationoutlinesscaleproblemrootcausesactionplanpopulationsobjectivesdeclarationincluderaisingawarenessaddressingsystemicbarriersadvocatingevidence-basedpoliciesinterventionslimitedpeoplecollaborativeeffortsaimmitigateburdensecurehealthierfuturedeclaration:frameworkcombatepidemicyoung-onsettypeAbdominalobesityObesityPreventionSouthYoung-onset

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