- Luk���� Fleischhans: Clinic of Infectious Diseases, Bulovka University Hospital, 1st, 2nd and 3rd Faculty of Medicine, Charles University, Czech Republic, e-mail: lukas.fleischhans@bulovka.cz.
In this short communication we describe the phenomenon of multidrug-resistant HIV-1 infection, possible causes and treatment op-tions in these cases. The case report presents the successful use of a drug lenacapavir in a non-adherent patient with HIV infection trea-ted at the HIV center of the Clinic of Infectious Diseases, University Hospital Bulovka, Prague.