OBJECTIVE: To identify specific tendon morphologies on ultrasonography of the Achilles tendon (AT) that later develop time-loss injury. DESIGN: Blinded post hoc analysis of a 2-year prospective, observational study of 944 AT sonographic videos to identify morphologic characteristics of diagnosed Achilles tendinopathies associated with future time-loss injury. The second year was used to validate the findings from the first year. SETTING: N/A. PATIENTS/PARTICIPANTS: Four hundred seventy-three National Collegiate Athletic Association student-athletes from 3 institutions over 2 years of data collection (57.7% females; 20.1 �� 1.6 years of age; 23.1 �� 2.8 kg/m2 of body mass index; 9.4 �� 3.6 years of sport experience). INTERVENTIONS/ASSESSMENT OF RISK FACTORS: Particular tendon morphologies were used to develop 3 ultrasonographic imaging rules that were used to predict AT injury leading to time loss in sport. MAIN OUTCOME MEASURES: Positive predictive value (PPV) and negative predictive values of particular tendon morphologies associated with the development of time-loss injury within 1 year. RESULTS: One of 3 morphologies, a deep mid-substance focal hypoechogenic area, was validated on 2 separate data sets and found to have a 33.3% PPV in both years for the development of time-loss injury. CONCLUSION: Results suggest a specific phenotype of sonographic abnormality of the AT that suggests a 1-in-3 chance of developing time-loss injury within a year. Detecting abnormality of future AT before symptoms develop may allow for rehabilitation strategies to prevent or reduce time-loss.
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Grants
UL1TR002538/PAC-12, National Center for Advancing Translational Sciences