Mycosis fungoides unveiled following dupilumab treatment in a patient with a history of atopic dermatitis. Usefulness of HFUS in monitoring skin features. A review with a case report.

Hanna Cisoń, Wiktor Cisoń, Barbara Białynicka-Birula, Marianna Suseł, Rafał Białynicki-Birula, Jacek C Szepietowski
Author Information
  1. Hanna Cisoń: Department of Dermatology, Venereology, and Allergology, Wroclaw Medical University, Wroclaw, Poland.
  2. Wiktor Cisoń: Experimental Dermatology Circle, Student Scientific Society of Wroclaw Medical University, Wroclaw, Poland.
  3. Barbara Białynicka-Birula: Experimental Dermatology Circle, Student Scientific Society of Wroclaw Medical University, Wroclaw, Poland.
  4. Marianna Suseł: Experimental Dermatology Circle, Student Scientific Society of Wroclaw Medical University, Wroclaw, Poland.
  5. Rafał Białynicki-Birula: Department of Dermatology, Venereology, and Allergology, Wroclaw Medical University, Wroclaw, Poland.
  6. Jacek C Szepietowski: Department of Dermatology, Venereology, and Allergology, Wroclaw Medical University, Wroclaw, Poland.

Abstract

Dupilumab has revolutionized atopic dermatitis (AD) treatment, but concerns arise about its potential link to cutaneous T-cell lymphomas (CTCL). This review explores CTCL occurrence post-dupilumab therapy in AD and its potential therapeutic effects. A case study of a 76-year-old patient with severe AD treated with dupilumab, developing erythroderma revealing mycosis fungoides (MF), underscores the need to understand associated mechanisms and risk factors for safe dupilumab use. This case also highlights the utility of the high-frequency ultrasound in monitoring cutaneous manifestations in patients with MF.

Keywords

References

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Word Cloud

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