ObjectiveLittle is known about the actual practice of self-prescription among physicians, especially with regard to potentially habit-forming drugs. This study was conducted to provide a description of self-prescription of opioids, sedative-hypnotics, and other psychotropic medications among all physicians in South Korea.MethodsThe self-prescription data on physicians from 2020 to 2023 were obtained from the Ministry of Food and Drug Safety. The prevalence of self-prescription and the average number of pills of self-prescribed potentially habit-forming drugs were presented in comparison with the prescription of these drugs among the general population.ResultsThe total number of practicing physicians in Korea ranged from 110,492 in 2020 to 118,951 in 2023. About seven percent of practicing physicians self-prescribed opioids, sedative-hypnotics, or other potentially habit-forming drugs, which was less than one fifth the proportion of prescription of these types of drugs among the general population. Zolpidem was the most commonly self-prescribed medication, with other sedatives, anxiolytics, and appetite suppressants also being frequently self-prescribed. Although the prevalence of self-prescription among physicians was lower than the prevalence of similar prescriptions in the general population, the number of pills of these medications per physician who self-prescribed was higher than that prescribed in the general population.ConclusionsDespite lower prevalence of self-prescription of opioids, sedative-hypnotics, and other potentially habit-forming drugs compared to prescriptions of these medications given out to the general population, the higher number of units of these self-prescribed drugs compared to prescriptions among the general population suggests that self-prescribing could be associated with utilization of more potentially habit-forming drugs than necessary, at least for some physicians. If these results are confirmed, closer monitoring of such self-prescribing habits among physicians in South Korea may be needed.