Reporting and incorporation of social risks in low back pain and exercise studies: A scoping review.

Andrew Bernstetter, Nicole H Brown, Brandon Fredhoff, Daniel I Rhon, Chad Cook
Author Information
  1. Andrew Bernstetter: Bellin College, Doctor of Science in Physical Therapy Program, 3201 Eaton Road, Green Bay, WI, 54311, USA; South College, Doctor of Physical Therapy Program, 400 Goody's Lane, Knoxville, TN, 37922, USA. Electronic address: andrew.bernstetter@bellincollege.edu.
  2. Nicole H Brown: Bellin College, Doctor of Science in Physical Therapy Program, 3201 Eaton Road, Green Bay, WI, 54311, USA. Electronic address: nicole.brown@bellincollege.edu.
  3. Brandon Fredhoff: Bellin College, Doctor of Science in Physical Therapy Program, 3201 Eaton Road, Green Bay, WI, 54311, USA. Electronic address: brandon.fredhoff@bellincollege.edu.
  4. Daniel I Rhon: Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA. Electronic address: daniel.rhon@usuhs.edu.
  5. Chad Cook: Duke University, Department of Orthopaedics, 311 Trent Drive, Durham, NC, 27710, USA. Electronic address: chad.cook@duke.edu.

Abstract

BACKGROUND: Exercise is a common intervention for low back pain, but its effect sizes are small to modest. Social risk factors significantly influence health outcomes, yet their consideration in randomized controlled trials on exercise for low back pain is often neglected. Determining their relationship to outcomes may provide better insight into exercise effectiveness.
OBJECTIVES: To assess the reporting of social risk factors (SRFs) in randomized controlled trials (RCTs) of exercise interventions for low back pain (LBP) in adults and explore associations between SRFs and outcomes.
DESIGN: Scoping Review.
METHODS: The databases MEDLINE, CINAHL and Cochrane were searched for studies published between January 2014 to March 2025. RCTs were included if exercise was the primary intervention for LBP treatment and had a minimum follow-up of 12 weeks. A planned analysis of SRF and outcome associations was not conducted due to insufficient data.
RESULTS: A total of 10,292 studies were identified and 157 studies included. Fewer than half (47.1 %) reported any SRFs at baseline. Socioeconomic position (42.7 %) was most frequently reported, followed by social relationships (17.8 %), race/ethnicity/cultural context (8.3 %), residential/community context (1.3 %), and gender (0.6 %). Four studies incorporated SRFs in their outcome analyses; one examined associations with outcomes and found no significant association.
CONCLUSION: SRFs are underreported in RCTs of exercise interventions for LBP and are rarely analyzed in relation to primary outcomes, limiting our understanding of their impact. Future trials should prioritize collecting and reporting SRFs at baseline and incorporating them in outcome analyses to assess their influence on outcomes.

Keywords

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Created with Highcharts 10.0.0outcomesexerciseSRFs%backpainlowstudiestrialssocialRCTsLBPassociationsoutcomeExerciseinterventionSocialriskfactorsinfluencehealthrandomizedcontrolledassessreportinginterventionsincludedprimary1reportedbaseline8context3analysesBACKGROUND:commoneffectsizessmallmodestsignificantlyyetconsiderationoftenneglectedDeterminingrelationshipmayprovidebetterinsighteffectivenessOBJECTIVES:adultsexploreDESIGN:ScopingReviewMETHODS:databasesMEDLINECINAHLCochranesearchedpublishedJanuary2014March2025treatmentminimumfollow-up12weeksplannedanalysisSRFconducteddueinsufficientdataRESULTS:total10292identified157Fewerhalf47Socioeconomicposition427frequentlyfollowedrelationships17race/ethnicity/culturalresidential/communitygender06FourincorporatedoneexaminedfoundsignificantassociationCONCLUSION:underreportedrarelyanalyzedrelationlimitingunderstandingimpactFutureprioritizecollectingincorporatingReportingincorporationrisksstudies:scopingreviewLowRehabilitationdeterminants

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