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Journal of sleep research
Mar 24, 2025; e70047.

Management of Adult Obstructive Sleep Apnoea: Many Questions, Not Enough Answers!

Maria Stanczyk, Walter T McNicholas, Dirk A Pevernagie, Renata L Riha, Silke Ryan
Author Information
  1. Maria Stanczyk: Pulmonary and Sleep Disorders Unit, St. Vincent's University Hospital, Dublin, Ireland.
  2. Walter T McNicholas: Pulmonary and Sleep Disorders Unit, St. Vincent's University Hospital, Dublin, Ireland. ORCID
  3. Dirk A Pevernagie: Department of Respiratory Diseases, AZ Delta, Roeselare, Belgium. ORCID
  4. Renata L Riha: Department of Sleep Medicine, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, Scotland. ORCID
  5. Silke Ryan: Pulmonary and Sleep Disorders Unit, St. Vincent's University Hospital, Dublin, Ireland. ORCID
PMID: 40129215 DOI: 10.1111/jsr.70047

Abstract

Obstructive sleep apnoea (OSA) conveys a substantial global public burden due to its high prevalence and causative relationship with cardiometabolic diseases. The current diagnostic reliance on the apnoea/hypopnoea index (AHI) is insufficient to address the complex, multifaceted condition, and a revision of the standard criteria is urgently needed. Together with a better understanding of the clinical, pathophysiological, and sleep diagnostic phenotypic characteristics, this will pave the way to personalised, holistic treatment approaches.

Keywords

CPAP cardiometabolic complications obstructive sleep apnoea phenotyping

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