Comprehensive geriatric assessment (CGA) is recommended for the evaluation of older patients with hematological malignancies. We investigated the association between CGA and mortality during hospitalization and at 1-year follow-up. Frailty was assessed by FRAIL scale, nutritional status by Mini-Nutritional Assessment-Short Form (MNA-SF), sarcopenia risk status by SARC-F. The Haema-Oncology Frailty (HOF) and Geriatric-8 (G8) scores were calculated prior to treatment. Most of the participants had malnutrition or risk of malnutrition based on the MNA-SF score. Half of the participants had risk of sarcopenia (���=���42, 50%). According to the FRAIL score, 51.2% (n:43) of the patients were FRAIL and 38.1% (n:32) were pre-FRAIL. Frailty was identified in 42.9% (���=���36) (HOF scores). Frailty (���=���0.007) and sarcopenia risk (���=���0.044) were linked to in-hospital mortality, the risk of 1-year mortality increased with higher HOF scores (���=���0.040). Findings from this study support the use of the FRAIL scale, SARC-F, and HOF score in clinical settings.