The demand for safe and effective surface disinfection solutions in the perioperative has led to the development of technologies beyond traditional chemical disinfectants, which are often associated with limitations including improper application, harmful residues, and environmental risks. Ultraviolet C (UVC) light has emerged as a powerful, chemical-free, and reusable alternative capable of neutralizing a wide range of pathogens without leaving residual contaminants. Despite its potential, conventional UVC technologies face limitations, including inconsistent coverage, user-dependent efficacy, and safety concerns related to exposure times. This paper provides a comprehensive comparison of various UVC disinfection technologies, highlighting their unique features, applications, and limitations in the perioperative period. Among these, the UVCeed Mobile UVC Disinfection Device (UVCeed, LLC, Effingham, Illinois) stands out as a novel innovation that transcends the capabilities of traditional UVC tools. By integrating cutting-edge augmented reality (AR), artificial intelligence (AI), and gamification, UVCeed enhances user safety, optimizes disinfection accuracy, and ensures an intuitive, engaging experience. Its real-time visual feedback and intelligent exposure control address the critical gaps in earlier UVC technologies. UVCeed's transformative approach sets a new benchmark in surface disinfection, offering unparalleled effectiveness, user-friendliness, and environmental sustainability across healthcare, consumer, and industrial applications.