Plant
Editosome
Database
Summary
| Editing Factor: | EMP18 |
| Synonym: | Empty Pericarp18 |
| Description: | Null mutation of Emp18 arrests embryo and endosperm development at an early stage in maize, resulting in embryo lethality; Mutants are deficient in the cytidine (C)-to-uridine (U) editing at atp6-635 and cox2-449, which converts a Leu to Pro in ATP6 and a Met to Thr in Cox2; The atp6 gene encodes the subunit a of F1 Fo -ATPase; The Leu to Pro alteration disrupts an α-helix of subunit a, resulting in a dramatic reduction in assembly and activity of F1 Fo -ATPase holoenzyme and an accumulation of free F1 -subcomplex |
| Protein Family: | PPR |
| Subclass: | DYW |
| Physical Interaction: | NA |
| Construct Structure: | PLS-E1/E2-E+-DYW |
| Gene ID & Species: | GRMZM2G471348 (Zea mays) |
| Edited Gene(s): | atp6 cox2 |
| Editing Type(s): | C-to-U (6) |
| Publication(s): |
[1] EMP18 functions in mitochondrial atp6 and cox2 transcript editing and is essential to seed development in maize., The New phytologist, 2019. [PMID=30168136] |
Editing Details
| Species | Gene ID | Organelle | Edited Gene | Position | Region | Nuclear Genome | Organelle Genome | Other Position Region | Other Position | Editing Type | Codon | Amino Acid | Molecular Effect | Experiment Details | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Zea mays | GRMZM2G471348 | Mitochondrion | atp6 | 635 | CDS | NA | NA | NA | NA | C-to-U | CCG=>CUG | P=>L | Recoding |
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| Zea mays | GRMZM2G471348 | Mitochondrion | cox2 | 449 | CDS | NA | NA | NA | NA | C-to-U | ACG=>AUG | T=>M | Recoding |
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Last update: Feb 2026
(version 2.0)