TWAS Atlas Version 2.0

Transcriptome-Wide Association Studies (TWAS) Atlas is a comprehensive knowledgebase of transcriptome-wide association studies, integrating trait-associated transcriptome signals from TWAS publications and GWAS datasets, along with the construction of TWAS knowledge graph to provide reliable and practical resource for researchers.

e.g. Lung Cancer; EFO:0004339; RBM6; ENSG00000004534; 31341166

Traits
590

Associations
676,198

Genes
24,870

Tissues
164

Publications
424

Datasets
171

  Latest News

  •   TWAS Atlas version 2.0 was online and the knowledge graph was updated with TWAS associations.  --2025/06/25

  •   An interactive Manhattan plot developed to visualize trait-associated genes based on TWAS association was included.  --2025/06/12

  •   Four new complementary analysis like Enrichment analysis, SMR, Colocalization and Fine-mapping results were available.  --2025/06/01

  •   A total of 676,198 TWAS associations were obtained from 424 publications and 171 datasets, covering 590 traits and 24,870 genes.  --2025/05/15

  •   TWAS Atlas version 1.0 was online on 2022-05-15 and knowledge graph was constructed with curated associations.  --2022/05/15

  •   A total of 401,226 TWAS associations were curated from 200 publications, covering 257 traits and 22,247 genes. --2022/04/25

  Citation and Contact

  • Please cite our database as follows:

  • "TWAS atlas 2.0: an updated data resource for transcriptome-wide association studies . Nucleic Acids Research, 2025 [PMID=41251136]."

  • "TWAS Atlas: a curated knowledgebase of transcriptome-wide association studies. Nucleic Acids Research, 2023 [PMID=36243959]."

  • Contact us: twas(AT)big.ac.cn

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