| Gene Symbol | LRCH1 |
| Description | leucine rich repeats and calponin homology domain containing 1 |
| Ensembl ID | ENSG00000136141.14 |
| Location | chr13: 46553168 - 46753040 |
| Cytogenetic Region | 13q14.13-q14.2 |
| Strand | + |
| Gene Type | protein_coding |
| Also Known As | CHDC1; NP81 |
| Summary | This gene encodes a protein with a leucine-rich repeat and a calponin homology domain. Polymorphism ... |
| Links To |
Reported Trait | Mapped Trait | Tissue | Gene Symbol | Ensembl ID | Gene Type | Method/Software | Effect Size | P-value | Publication |
|---|---|---|---|---|---|---|---|---|---|
| Stroke | Stroke | Adipose | LRCH1 | ENSG00000136141.14 | protein-coding | FUSION | -4.81E+00 | 1.54E-06 | TWASP000034 |
| Standing Height | Body Height | Brain Cortex | LRCH1 | ENSG00000136141.14 | protein-coding | PrediXcan | 5.53E+00 | 3.19E-08 | TWASP000056 |
| Standing Height | Body Height | Nerve Tibial | LRCH1 | ENSG00000136141.14 | protein-coding | PrediXcan | 6.13E+00 | 8.92E-10 | TWASP000056 |
| Body Height | Body Height | Cross-tissue | LRCH1 | ENSG00000136141.14 | protein-coding | Summary-MultiXcan(S-MultiXcan) or UTMOST | - | 1.03E-11 | TWASP000165 |
| Standing Height | Body Height | Muscle Skeletal | LRCH1 | ENSG00000136141.14 | protein-coding | Probabilistic Transcriptome-Wide Association(PTWAS) | - | 1.32E-10 | TWASP000141 |
| Height | Body Height | Muscle Skeletal | LRCH1 | ENSG00000136141.14 | protein-coding | Probabilistic Transcriptome-Wide Association(PTWAS) | - | 4.11E-07 | TWASP000141 |
| Systolic Blood Pressure | Systolic Blood Pressure | Cross-tissue | LRCH1 | ENSG00000136141.14 | protein-coding | MultiXcan | - | 5.94E-07 | TWASP000056 |
| High Light Scatter Reticulocyte Count | Reticulocyte Count | Aortic Artery | LRCH1 | ENSG00000136141.14 | protein-coding | Probabilistic Transcriptome-Wide Association(PTWAS) | - | 6.88E-06 | TWASP000141 |
| Standing Height | Body Height | Cross-tissue | LRCH1 | ENSG00000136141.14 | protein-coding | MultiXcan | - | 7.22E-16 | TWASP000056 |
| Height | Body Height | Nerve Tibial | LRCH1 | ENSG00000136141.14 | protein-coding | Summary-MultiXcan(S-MultiXcan) | - | 8.04E-08 | TWASP000056 |
Gene Symbol | SNP | Ref Allele | Alt Allele | SNP Location | Effect Size | P-value | Tissue |
|---|---|---|---|---|---|---|---|
| LRCH1 | rs4942570 | A | G | chr13:46676769 | -0.182611 | 3.12803e-13 | Adipose_Subcutaneous |
| LRCH1 | rs2005053 | T | C | chr13:46578807 | 0.20977 | 1.39441e-06 | Cells_EBV-transformed_lymphocytes |
| LRCH1 | rs9534439 | T | C | chr13:46617914 | -0.137096 | 7.543e-07 | Esophagus_Muscularis |
| LRCH1 | rs4245340 | A | G | chr13:46675725 | 0.393419 | 2.12769e-09 | Liver |
| LRCH1 | rs4942567 | A | G | chr13:46644699 | -0.156218 | 1.52536e-07 | Testis |
