e.g., PRJCA000229; PRJNA784038; human
Accession PRJCA015895
Title CD24hiCD27+Bregs within mLN orchestrate the stemness and multi-drug resistance of breast cancer cells via direct contact-interaction
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Homo sapiens
Description Single cell sequencing was performed on puncture specimens of neoadjuvant sensitive primary breast cancer and paired therapy-resistant metastatic lymph node to analyze key cell subsets associated with treatment resistance in the metastatic lymph node microenvironment .
Sample scope Single cell
Release date 2023-10-08
Publication
PubMed ID Article title Journal name DOI Year
37831062 CD24hiCD27+Bregs within metastatic lymph nodes promote multi-drug resistance in breast cancer Clinical Cancer Research 10.1158/1078-0432.CCR-23-1759 2023
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 82273275
Submitter Chao Ni (davenc@163.com)
Organization The Second Affiliated Hospital, Zhejiang University School of Medicine
Submission date 2023-03-28

Project Data

Resource name Description
GSA-Human (1)-
HRA004270CD24hiCD27+ Breg cells within mLN orchestrate the stemness and drug resistance of breast cancer cells via direct contact- interaction