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Riboviria isolate Culex/MsambweniMCF1/2021/Hubei_virus:segment:1 Putative serine protease (serineprotease1), Serine protease (serineprotease2), and RNA dependent RNA polymerase (RdRp) genes, complete cds.

Accession:
C_AA111996.1

Seq-submit ::= {
  sub {
    contact {
      contact {
        name name {
          last "Xia",
          first "Han",
          middle "",
          initials "",
          suffix "",
          title ""
        },
        affil std {
          affil "Wuhan Institute of Virology, Chinese Academy of Sciences",
          div "Microbial Resource and Bioinformatic Center",
          city "Wuhan",
          country "China",
          street "NO.44 Xiaohongshan",
          email "hanxia@wh.iov.cn",
          postal-code "430071"
        }
      }
    },
    cit {
      authors {
        names std {
          {
            name name {
              last "Xia",
              first "Han",
              initials "H."
            }
          }
        },
        affil std {
          affil "Wuhan Institute of Virology, Chinese Academy of Sciences",
          div "Microbial Resource and Bioinformatic Center",
          city "Wuhan",
          sub "Hubei",
          country "China",
          street "NO.44 Xiaohongshan",
          postal-code "430071"
        }
      },
      date std {
        year 2025,
        month 7,
        day 15
      }
    },
    subtype new,
    tool "table2asn 1.28.1094"
  },
  data entrys {
    set {
      class nuc-prot,
      descr {
        source {
          org {
            taxname "Riboviria",
            orgname {
              mod {
                {
                  subtype isolate,
                  subname "Culex/MsambweniMCF1/2021/Hubei_virus:segment:1"
                },
                {
                  subtype nat-host,
                  subname "Culex; Host_sex: Female"
                },
                {
                  subtype metagenome-source,
                  subname "mosquito metagenome"
                }
              },
              gcode 1
            }
          },
          subtype {
            {
              subtype country,
              name "Kenya: Msambweni"
            },
            {
              subtype environmental-sample,
              name ""
            },
            {
              subtype collection-date,
              name "2021"
            },
            {
              subtype metagenomic,
              name ""
            }
          }
        },
        user {
          type str "StructuredComment",
          data {
            {
              label str "StructuredCommentPrefix",
              data str "##Assembly-Data-START##"
            },
            {
              label str "Assembly Method",
              data str "Megahit v. 1.2.9"
            },
            {
              label str "Sequencing Technology",
              data str "Illumina"
            },
            {
              label str "StructuredCommentSuffix",
              data str "##Assembly-Data-END##"
            }
          }
        },
        create-date std {
          year 2025,
          month 7,
          day 15
        }
      },
      seq-set {
        seq {
          id {
genbank { accession "C_AA111996", version 1}, gi 0670650651119961
          },
          descr {

        user {
            class "1.0",
            type str "AutodefOptions",
            data {
                {label str "UseLabels", data bool TRUE},
                {label str "LeaveParenthetical", data bool TRUE},
                {label str "SpecifyNuclearProduct", data bool TRUE},
                {label str "MaxMods", data int 0},
                {label str "FeatureListType", data str "List All Features"},
                {label str "MiscFeatRule", data str "Delete"},
                {label str "HIVRule", data str "WantBoth"},
                {label str "ModifierList",
                    data fields { {label str "OrgMods", num 1,
                            data strs {"isolate" }}}}}},
        
            molinfo {
              biomol genomic
            },
            user {
              type str "Submission",
              data {
                {
                  label str "AdditionalComment",
                  data str "GenBase"
                }
              }
            }
          },
          inst {
            repr raw,
            mol rna,
            length 3260,
            topology linear,
            strand ss,
            seq-data ncbi4na '481141122112148144484121818148224144128118828418
482111118822182181841182182488281882182182428884148814411882118182888111418188
414841411121882484188822142488818882888111418188411882281128211424184184118141
124184188218184184411888884121821411881482282441281818482122281284884488288122
281484421888118482181112221842218114428184481184188148888482128188884488422284
48814182488142181288442228144881818841828F424882422828888481428144884441244882
248812844118228888818822288111412228118812418884282181882812182124484884188484
18842118481888814824414121481211224424211421841181881828228112821142844F114888
414848414111428184221118142118818414181488228488884222824888211428128482281488
821881418441488111812428411118448211842888844482412411448884884128824428218481
188411441818414818842842181812244418411111218114481411288111128821428888411488
441214448418812422842842141418228181214181124214144281442884828111441111282824
118484428188214111418828441881142482118488121428888441111241821182442882281118
214218224211888441888488411818121448148122428111441888148441424228818818888441
24118418888844818421888144142841282F482112181442818412424421888884114148411288
141221142244488188114824281188112288211211411418148428148844282488414214884412
144211418418482211812844211828228888412222824411888114488241488442112184812212
188481418448428484881412414182184142111144111188144114118484441114181418812288
828411881144481214111244182214112224882882288284114144114884141884884184114144
114144882212114142282244811282242144142282244841282214412288242112282821884184
812241222821182284281182428184114124282811888214812842484421841841114148824421
411288214888181214228841442844141114114284824141218812214112282812112244114884
841142142282114284281142112214114814821114814184118842288814282242484124281841
218821124188244411128842821444282244284824184284444222F84421144848482142144842
284882148122114422142241818182222111844828882218122242212288844841188122181844
118222428248241842284882242111124814288821242421212111411121411121412414284222
422112142141141124112814142148121412142428124482281842111184424484241228212142
142282241222241242884488241224141488211211242118411441418141818411114812822844
181884818188412881881844182411211842421418888844884411844818442284841222841814
448182118448814421121848211188124888841821188428442444111822818114841841818111
448888848811421141422221211188411411118821141844112181824128818814842248814288
118841212488818841214118828488842184418142224148221188441812148844811112822484
828148144484414222848114444244184424842818121411814188842111882122148848184228
141224882242884441884412448821444481888448141828284488121488828841111828222148
811822822111184484418282148818411428214488211428888488841441848284488811488841
141844112124848811421418412224844848818411114844484281888112818818828811814888
414221414288488421281218142811228224484844124422218442841111121122181F82818144
841841812448221141142288241884428441141281848211121128841418488444148812448211
144842811148221111284448841488242144288284888841844111112184881822442181884421
111188828888811228814821812421124828844441412488488114881821181288481248811841
422848818481241488818284214448442824241488444822221188248228422811488441142228
241818818411821122111884188248881884448828288228288114484141411814441841488442
11121888212441'H
          },
          annot {
            {
              data ftable {
                {
                  id local id 2,
                  data gene {
                    locus "serineprotease1"
                  },
                  location int {
                    from 192,
                    to 1478,
                    strand plus,
                    id gi 0670650651119961
                  },
                  xref {
                    {
                      id local id 1
                    }
                  }
                },
                {
                  id local id 3,
                  data rna {
                    type mRNA,
                    ext name "Putative serine protease"
                  },
                  location int {
                    from 192,
                    to 1478,
                    strand plus,
                    id gi 0670650651119961
                  },
                  xref {
                    {
                      data gene {
                        locus "serineprotease1"
                      }
                    },
                    {
                      id local id 1
                    }
                  }
                },
                {
                  id local id 5,
                  data gene {
                    locus "serineprotease2"
                  },
                  location int {
                    from 1589,
                    to 2125,
                    strand plus,
                    id gi 0670650651119961
                  },
                  xref {
                    {
                      id local id 4
                    }
                  }
                },
                {
                  id local id 6,
                  data rna {
                    type mRNA,
                    ext name "Serine protease"
                  },
                  location int {
                    from 1589,
                    to 2125,
                    strand plus,
                    id gi 0670650651119961
                  },
                  xref {
                    {
                      data gene {
                        locus "serineprotease2"
                      }
                    },
                    {
                      id local id 4
                    }
                  }
                },
                {
                  id local id 8,
                  data gene {
                    locus "RdRp"
                  },
                  location int {
                    from 2122,
                    to 3192,
                    strand plus,
                    id gi 0670650651119961
                  },
                  xref {
                    {
                      id local id 7
                    }
                  }
                },
                {
                  id local id 9,
                  data rna {
                    type mRNA,
                    ext name "RNA dependent RNA polymerase"
                  },
                  location int {
                    from 2122,
                    to 3192,
                    strand plus,
                    id gi 0670650651119961
                  },
                  xref {
                    {
                      data gene {
                        locus "RdRp"
                      }
                    },
                    {
                      id local id 7
                    }
                  }
                }
              }
            }
          }
        },
        seq {
          id {
genbank { accession "C_AAL25808", version 1}, gi 067065065076258081
          },
          descr {
            title "MAG: Putative serine protease [Riboviria]",
            molinfo {
              biomol peptide,
              tech concept-trans
            }
          },
          inst {
            repr raw,
            mol aa,
            length 428,
            seq-data iupacaa "MMNRTMIHMMEFLTSELVLGLYVTLLLVLTLVAFNVINPCHKAMVMIS
FVTILVALVRSLAYLALGYIDLAFASFVARLGRFRYWNPFYSLKDPNYDLLIFYITVLIVIAMYFSRRQYNRRKHEYY
LLTQAGKFECEKAMPNSNYEIVPVLPSFQATVLVSLDGVKYAENGQCFWVDEGLLTSAHVIEGYEYCCIYRDEKHKVE
LKTSAFEVGQGDYACCRDPIQITQRLGLSKGKLSNVAIQKDSGLSVNVTAFGKRSIGFLNQHPQFGFVEYTGSTAKGF
SGAPYYFGRMIFGMHLGADSVNIGYDAAFLKSELRPSRVIKSLINLQQEDSASWLVEQLDRQDDVQYWQSPFDPSEFK
VRVGNMYHIVDGAVLDEIMSKRKIRKNVGKIDYLSELRVQKRIQNPFFLLKRKLRLLMKRKRFHKSLR"
          },
          annot {
            {
              data ftable {
                {
                  data prot {
                    name {
                      "Putative serine protease"
                    }
                  },
                  location int {
                    from 0,
                    to 427,
                    id gi 067065065076258081
                  }
                }
              }
            }
          }
        },
        seq {
          id {
genbank { accession "C_AAL25809", version 1}, gi 067065065076258091
          },
          descr {
            title "MAG: Serine protease [Riboviria]",
            molinfo {
              biomol peptide,
              tech concept-trans
            }
          },
          inst {
            repr raw,
            mol aa,
            length 178,
            seq-data iupacaa "MMKEFGRTSVYTALRLEKEAVETLPEPLQPEVVKQPQAAKQPEVVKVD
ELPLAPRDAMTFNDSGNLLRAPAVDAGAXGKVCQQVPVQYQGQPIYPQMVFPYPPPLVNYHMESRSSMPVPQNVAFTR
TQRNRNRRAARQQQKNELEQYRQRYGPMQNGGATSQQPPTPTLGSTESSTTQ"
          },
          annot {
            {
              data ftable {
                {
                  data prot {
                    name {
                      "Serine protease"
                    }
                  },
                  location int {
                    from 0,
                    to 177,
                    id gi 067065065076258091
                  }
                }
              }
            }
          }
        },
        seq {
          id {
genbank { accession "C_AAL25810", version 1}, gi 067065065076258101
          },
          descr {
            title "MAG: RNA dependent RNA polymerase [Riboviria]",
            molinfo {
              biomol peptide,
              tech concept-trans
            }
          },
          inst {
            repr raw,
            mol aa,
            length 356,
            seq-data iupacaa "MKEIDMKSTPGYCILTYYGSNNAQIFGWNGMACDPDRVSMVRQHVKLR
FDQLLAGNPISDDIKVFVKQEPHKLKKIQDGTYRLISAVSLIDTFIDRILFAWIARVQLDTVGKTPCLVGWSPVRGGW
RAIQNRFANSPVVCLDRSAWDWTVQGYLVDLWLQFLENLPVNPPKWWISVMKLRFKLLFEDVWFKFEDGTRVKQMTRG
VMKSGCYLTIILNSLSQSLLHYIANLRCGRPMAEKQPXSIGDDTVQEAFDWLEDYVKQLEMLGVTVKGAKVQNWVEFA
GFCFDGKTCYPAYWQKFLFNLSHTQRLGETLLSYQYLYVNEPVMYEFICRVARELGPQFVLPKLEALDIMNQPN"
          },
          annot {
            {
              data ftable {
                {
                  data prot {
                    name {
                      "RNA dependent RNA polymerase"
                    }
                  },
                  location int {
                    from 0,
                    to 355,
                    id gi 067065065076258101
                  }
                }
              }
            }
          }
        }
      },
      annot {
        {
          data ftable {
            {
              id local id 1,
              data cdregion {
                frame one,
                code {
                  id 1
                }
              },
              product whole gi 067065065076258081,
              location int {
                from 192,
                to 1478,
                strand plus,
                id gi 0670650651119961
              },
              xref {
                {
                  id local id 2
                },
                {
                  id local id 3
                }
              }
            },
            {
              id local id 4,
              data cdregion {
                frame one,
                code {
                  id 1
                }
              },
              product whole gi 067065065076258091,
              location int {
                from 1589,
                to 2125,
                strand plus,
                id gi 0670650651119961
              },
              xref {
                {
                  id local id 5
                },
                {
                  id local id 6
                }
              }
            },
            {
              id local id 7,
              data cdregion {
                frame one,
                code {
                  id 1
                }
              },
              product whole gi 067065065076258101,
              location int {
                from 2122,
                to 3192,
                strand plus,
                id gi 0670650651119961
              },
              xref {
                {
                  id local id 8
                },
                {
                  id local id 9
                }
              }
            }
          }
        }
      }
    }
  }
}
资助信息
资助标题:Research on Discovery of Arthropod-borne Viral Pathogens and Infection Transmission Risk
资助机构:Ministry of Science and Technology of the People's Republic of China (MOST)
资助项目:National Key Technologies R&D Program
资助标号:2023QNTJ-03
资助标题:Cross-border Vector-borne Disease Pathogen Surveillance and Port Application
资助机构:Ministry of Science and Technology of the People's Republic of China (MOST)
资助项目:National Key Technologies R&D Program
资助标号:2022YFC2302700
序列分析