HRA000188
Title:
Evolution under spatially-heterogeneous selection in solid tumors
Release date:
2022-01-13
Description:
Multi-stage tumorigenesis and clonal evolution model described previously indicate that solid tumor is temporally and spatially heterogeneous, samples collected at different time points or spatial positions providing various genetic information. Based on this, we performed three-dimensional micro-dissection and whole-genome sequencing (WGS) for two tumors at a relatively early stage to comprehensively trace the mutation evolutionary process of tumors and decipher their clonal distribution in three dimensions.
Data Accessibility:   
Controlled access Request Data
BioProject:
Study type:
Disease Study
Disease name:
liver cancer
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
DAC name:
HCC27 data
Contact person:
Xuemei Lu
Email:
xuemeilu@mail.kiz.ac.cn
Description:
WGS data of 25 tumor samples from one patient
Individuals & samples
Submitter:   Xuemei Lu / xuemeilu@mail.kiz.ac.cn
Organization:   Kunming Institute of Zoology, Chinese Academy of Sciences
Submission date:   2020-06-05
Requests:   -