e.g., HRA000087; HRA000150
HRA001665
Title:
Study on the Pathogenic Genes and the Tumor Immune Evasion Mechanism of Juvenile-onset Recurrent Respiratory Papillomatosis Based on Multi-omics
Release date:
2021-12-16
Description:
Juvenile-onset recurrent respiratory papillomatosis (JORRP) is a rare disease in children, caused by human papillomavirus (HPV) type 6 and 11. At present, it is believed that the high recurrence rate of JORRP is mediated by compromised anti-viral and anti-tumor immune responses. While the host pathogenic genes and the immune evasion mechanism of HPV promote its persistent and recurrent infection remains unknown. In this study, we intend to carry out multi-omics joint analysis of the genome transcriptome and proteome landscapes of tumor tissue and peripheral blood in JORRP by whole exome sequencing (WES), single-cell transcriptome profiling (single-cell RNA sequencing (scRNA-seq)) and mass cytometry.
Data Accessibility:   
Controlled access Request Data
BioProject:
Study type:
Disease Study
Disease name:
papillomavirus infectious disease
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
DAC name:
Commitee of JORRP
Contact person:
Wang Jun
Email:
trentxy@163.com
Description:
Commitee of JORRP answers to external reuqestors accordingly.
Individuals & samples
Individual Accession
Individual Name
Gender
Sample Accession
Sample Name
Sample Description
Individual Accession
Individual Name
Gender
Sample Accession
Sample Name
Sample Description
HRI177789JORRP 1femaleHRS317117HZB-LPHZB-LP
HRI177789JORRP 1femaleHRS317118HZB-PBMCHZB-PBMC
HRI177789JORRP 1femaleHRS317119HZB-tumorHZB-tumor
HRI177790JORRP 2maleHRS317120WYW-PBMCWYW-PBMC
HRI177791JORRP 3maleHRS317121WYX-LPWYX-LP
HRI177791JORRP 3maleHRS317122WYX-tumorWYX-tumor
HRI177792JORRP 4femaleHRS317123WZY-LPWZY-LP
HRI177792JORRP 4femaleHRS317124WZY-PBMCWZY-PBMC
HRI177792JORRP 4femaleHRS317125WZY-tumorWZY-tumor
HRI177793JORRP 5maleHRS317126YJQ-LPYJQ-LP
Showing 1 to 10 of 15 rows rows per page
Run accession
Files
Experiment
Experiment title
Platform
Sample
Run accession
Files
Experiment
Experiment title
Platform
Sample
HRR566298HRR566298_f1.fastq.gz (1.88 GB)HRX407918RNA-sequencing-1Illumina NovaSeq 6000HRS317117 (SAMC1979005)
HRR566298HRR566298_r2.fastq.gz (1.95 GB)HRX407918RNA-sequencing-1Illumina NovaSeq 6000HRS317117 (SAMC1979005)
HRR566299HRR566299_f1.fastq.gz (0.37 GB)HRX407919RNA-sequencing-2Illumina NovaSeq 6000HRS317118 (SAMC1979009)
HRR566299HRR566299_r2.fastq.gz (0.39 GB)HRX407919RNA-sequencing-2Illumina NovaSeq 6000HRS317118 (SAMC1979009)
HRR566300HRR566300_f1.fastq.gz (1.28 GB)HRX407920RNA-sequencing-3Illumina NovaSeq 6000HRS317119 (SAMC1979012)
HRR566300HRR566300_r2.fastq.gz (1.37 GB)HRX407920RNA-sequencing-3Illumina NovaSeq 6000HRS317119 (SAMC1979012)
HRR566301HRR566301_f1.fastq.gz (2.05 GB)HRX407921RNA-sequencing-4Illumina NovaSeq 6000HRS317120 (SAMC1979014)
HRR566301HRR566301_r2.fastq.gz (2.17 GB)HRX407921RNA-sequencing-4Illumina NovaSeq 6000HRS317120 (SAMC1979014)
HRR566302HRR566302_f1.fastq.gz (1.81 GB)HRX407922RNA-sequencing-5Illumina NovaSeq 6000HRS317121 (SAMC1979018)
HRR566302HRR566302_r2.fastq.gz (1.86 GB)HRX407922RNA-sequencing-5Illumina NovaSeq 6000HRS317121 (SAMC1979018)
Showing 1 to 10 of 30 rows rows per page
Submitter:   Wang Jun / trentxy@163.com
Organization:   Beijing Tongren Hospital
Submission date:   2021-12-10
Requests:   -