In this study, we performed WGS, WGBS, RNA sequencing, and small RNA sequencing on tumor tissues as well as matched adjacent non-neoplastic tissues from ESCC patients to discover potential molecular subgroups. We present a comprehensive molecular profiling of ESCC with a focus on identifying novel molecular subgroups and functionally altered signaling pathways that may drive tumorigenesis and serve as prognostic or therapeutic signatures.
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Organization: National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
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HRA003533.xlsx