NGDC - GSA for Human

HRA008309

HRA008309.xlsx

Title:

Low Pass Whole Genome Sequencing for Detecting Chromosome Instability in Breast Cancer

Release date:

2024-09-29

Description:

The aim of this project is to evaluate the role of chromosomal instability (CIN) in the preoperative prediction of sentinel lymph node (SLN) metastasis in breast cancer patients. By analyzing low-pass whole-genome sequencing (LP-WGS) data in depth, we plan to explore the correlation between CIN and SLN metastasis and develop a CIN-based predictive model to improve the accuracy of preoperative assessment of lymph node metastasis risk in breast cancer patients. This project not only helps to improve the level of personalized treatment for breast cancer patients but may also provide new research ideas and methods for predicting lymph node metastasis in other types of tumors. By reducing unnecessary invasive examinations, this project is expected to improve patients' quality of life and provide a scientific basis for the rational allocation of medical resources.

Data Accessibility:

Controlled access Request Data

BioProject:

PRJCA029094

Study type:

Disease Study

Disease name:

female breast cancer

Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.

DAC NO.:

HDAC004567

DAC name:

DAC

Contact person:

Hao Hua

Email:

haohua410@tongji.edu.cn

Description:

DAC for project PRJCA029094

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