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<!-----------------title--------------------->
 
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{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
|style="width:50%; text-align:center; white-space:nowrap; color:#000"|
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<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div>
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<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki 1.0</div>
 
<div style="padding:0em; font-size:100%">[[:Category:Transcripts|106,063]] human long non-coding RNAs inside</div>
 
<div style="padding:0em; font-size:100%">[[:Category:Transcripts|106,063]] human long non-coding RNAs inside</div>
  
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*[[:Category:Transcripts|LncRNA Transcripts]]
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*[[:Category:Transcripts|Transcripts]]
 +
*[[:Category:Genes|Genes]]
 
*[[LncRNAWiki:Classification|Classification]]
 
*[[LncRNAWiki:Classification|Classification]]
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|style="width:15%;|
*[[:Category:Genes|Genes]]
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*[[LncRNAWiki:Featured|Featured LncRNAs]]
*[[Special:BLAST|BLAST]]
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*[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&biological_context=Disease Disease]
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*[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism= Function]
*[[LncRNAWiki:Download|Downloads]]
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*[[LncRNAWiki:FAQ|FAQ]]
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*[[LncRNAWiki:Small_proteins|Small Proteins]]
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*[http://bigd.big.ac.cn/lgc Prediction]
*[[File:New5.png]][[LncRNAWiki:Featured|Featured LncRNAs]]
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*[http://bigd.big.ac.cn/lncbook/blast BLAST]
*[[File:New5.png]][[LncRNAWiki:Small_proteins|Small Proteins]]
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|style="width:15%;|
*[[File:New5.png]][[LncRNAWiki:Disease|Diseases]]
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<div style="padding:0.5em 0.5em;">[[File:News2.png|center|150px|link=https://ngdc.cncb.ac.cn/lncrnawiki/]]</div>
 
|}
 
|}
 
 
<!---------------welcome Box----------------->
 
<!---------------welcome Box----------------->
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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<div style="padding:1em 0.5em;">
 
<div style="padding:1em 0.5em;">
 
{{LncRNAWiki:Summary}}
 
{{LncRNAWiki:Summary}}
<div style="padding:0.2em 0.5em;text-align:center;font-weight:bold;color:#2d2d2d;">''Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia''</div>
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<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an important component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
 
</div>
 
</div>
 
|}
 
|}
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
|-
 
|-
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<!-----------Featured lncRNAs------------>
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://lncrna.big.ac.cn/index.php/LncRNAWiki:Featured Featured lncRNAs]</div>
 +
<div style="padding:0.5em 0.5em;">[[File:Homepage-2020.png|center|500px|link=LncRNAWiki:Featured]]</div>
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 +
|style="padding:0px 4px;"|
 +
 
<!-----------Top 10 lncRNA-associated diseases------------>
 
<!-----------Top 10 lncRNA-associated diseases------------>
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:45%;"|
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [[LncRNAWiki:Disease|lncRNA-associated diseases]]</div>
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&biological_context=Disease lncRNA-associated diseases]</div>
  
 
<div style="padding:0.5em 0.5em;">
 
<div style="padding:0.5em 0.5em;">
 
''Diseases and their associated lncRNAs' counts are listed below.''
 
''Diseases and their associated lncRNAs' counts are listed below.''
 +
* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=hepatocellular%20cancer Hepatocellular cancer]: 361
  
* [[LncRNAWiki:Cancer|Cancer]]: 212
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=colorectal%20cancer Colorectal cancer]: 305
  
* [[LncRNAWiki:Nervous System Diseases|Nervous System Diseases]]: 37
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=lung%20cancer Lung cancer]: 296
  
* [[LncRNAWiki:Cardiovascular Diseases|Cardiovascular Diseases]]: 22
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=breast%20cancer Breast cancer]: 282
  
* [[LncRNAWiki:Congenital, Hereditary, and Neonatal Diseases and Abnormalities|Congenital, Hereditary, and Neonatal Diseases and Abnormalities]]: 21
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=oral%20squamous%20cell%20cancer Oral squamous cell cancer]: 234
  
* [[LncRNAWiki:Musculoskeletal Diseases|Musculoskeletal Diseases]]: 20
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=Gastric%20cancer Gastric cancer]: 233
  
* [[LncRNAWiki:Hemic and Lymphatic Diseases|Hemic and Lymphatic Diseases]]: 19
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=prostate%20cancer Prostate cancer]: 213
  
* [[LncRNAWiki:Endocrine System Diseases|Endocrine System Diseases]]: 18
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=b%20acute%20lymphoblastic%20leukemia%20with%20t B acute lymphoblastic leukemia with t(1;19)(q23;p13.3)]: 173
  
* [[LncRNAWiki:Mental Disorders|Mental Disorders]]: 14
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=papillary%20thyroid%20cancer Papillary thyroid cancer]: 157
  
* [[LncRNAWiki:Skin and Connective Tissue Diseases|Skin and Connective Tissue Diseases]]: 9
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=obesity Obesity]: 151
  
* [[LncRNAWiki:Nutritional and Metabolic Diseases|Nutritional and Metabolic Diseases]]: 9
 
  
 
</div>
 
</div>
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|}
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<!--------------main part two---------------->
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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|-
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<!-----------------Extensively curated---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
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{|style="width:100%;"
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Extensively curated</div>
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|style="width:33%;|
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* [[NONHSAT028508|''HOTAIR'']]
  
|style="padding:0px 4px;"|
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* [[ENST00000534336.1|''MALAT-1'']]
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 +
* [[NONHSAT017465|''H19'']]
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 +
* [[NONHSAT039745|''MEG3'']]
 +
 
 +
* [[ENST00000501122.2|''NEAT1'']]
  
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* [[ENST00000513868.2|''PVT1'']]
  
<!-----------Featured lncRNAs------------>
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* [[NONHSAT007663|''GAS5'']]
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:54.5%;"|
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Featured|Featured lncRNAs]]</div>
 
<div style="padding:0.5em 0.5em;">
 
<table>
 
<tr>
 
<td>[[File:Featured4.png|left|430px|link=LncRNAWiki:Featured]]</td>
 
<td valign="top">
 
Extensively curated:
 
  
* [[ENST00000609176.1|''AIRN'']]
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* [[Lnc-C9orf53-2:1|''CDKN2B-AS1'']]
  
* [[ABALON|''ABALON'']]
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* [[NONHSAT119717|''HOTTIP'']]
  
* [[ENST00000444200.1|''APOA1-AS'']]
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* [[NONHSAT113149|''7SK'']]
  
 +
|style="width:33%;|
 
* [[BANCR|''BANCR'']]
 
* [[BANCR|''BANCR'']]
  
* [[ENST00000502056.1|''CASC8'']]
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* [[BTG3-AS1|''BTG3-AS1'']]
  
* [[NONHSAT017465|''H19'']]
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* [[CERNA2|''CERNA2'']]
 +
 
 +
* [[FLICR|''FLICR'']]
 +
 
 +
* [[GUARDIN|''GUARDIN'']]
 +
 
 +
* [[LINC-ROR|''LINC-ROR'']]
 +
 
 +
* [[PINCR|''PINCR'']]
  
* [[NONHSAT028508|''HOTAIR'']]
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* [[PLUT|''PLUT'']]
  
 
* [[LUNAR1|''LUNAR1'']]
 
* [[LUNAR1|''LUNAR1'']]
  
* [[ENST00000534336.1|''MALAT-1'']]
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* [[Lnc-SRA1-1:1|''SRA'']]
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 +
|style="width:34%;|
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* [[NONHSAT017524|''KCNQ1OT1'']]
 +
 
 +
* [[NONHSAT076153|''PCGEM1'']]
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 +
* [[NONHSAT137541|''XIST'']]
 +
 
 +
* [[Lnc-EPCAM-1:2|''BCYRN1'']]
 +
 
 +
* [[NONHSAT084827|''TUG1'']]
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 +
* [[Lnc-OR10H5-1:1|''UCA1'']]
 +
 
 +
* [[NONHSAT107640|''HULC'']]
 +
 
 +
* [[NONHSAT129019|''PRNCR1'']]
  
* [[NONHSAT039745|''MEG3'']]
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* [[TP53COR1|''TP53COR1'']]
  
* [[NONHSAT137541|''Xist'']]
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* [[Lnc-CDKN1A-1:1|''PANDAR'']]
</td>
 
</tr>
 
</table>
 
</div>
 
 
|}
 
|}
  
<!--------------main part two---------------->
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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|-
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<!-----------------Function---------------------->
<!-----------------Small proteins---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;45%;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism= Functional mechanism]</div>
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Small_proteins|Small proteins]]</div>
 
<div style="padding:0.5em 0.5em;">[[File:SmallPRO-5.png|center|220px|link=LncRNAWiki:Small_proteins]]</div>
 
* [[LncRNAWiki:Small_proteins|'''9,387''']] lncRNAs potentially encoding small proteins
 
  
* '''2,246''' small proteins identified with high confidence, by considering protein instability, secondary structure and transmembrane helix
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<div style="padding:0.5em 0.5em;">
 +
''Functional mechanisms and their associated lncRNAs' counts are listed below.''
  
|style="padding:0px 4px;"|
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=ceRNA ceRNA]: 194
 +
* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Transcriptional%20regulation Transcriptional regulation]: 85
 +
* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Epigenetic%20regulation Epigenetic regulation]: 84
 +
* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Post-transcriptional%20regulation Post-transcriptional regulation]: 12
 +
* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Translational%20regulation Translational regulation]: 2
  
<!-----------------Classification---------------------->
 
  
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:54.5%;"|
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</div>
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Classification|Classification]]</div>
 
<div style="padding:0.5em 0.5em;">[[File:Classification.png|center|400px|link=LncRNAWiki:Classification]]</div>
 
 
|}
 
|}
  
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* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
 
* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
  
Related publications:
+
Related publication:
* [http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1060.full '''The BIG Data Center: from deposition to integration to translation'''.] (2017) ''Nucleic Acids Research'', 45:D18-24.
+
* [https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpbi.82 '''Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook'''.] '' Curr Protoc Bioinformatics 2019''.
* [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 '''On the classification of long non-coding RNAs'''.] (2013) ''RNA Biology'', 10:924-933.
 
 
</div>
 
</div>
  

Latest revision as of 10:38, 18 September 2021



Welcome to LncRNAWiki 1.0
106,063 human long non-coding RNAs inside
News2.png
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

LncRNAWiki, an important component of LncBook, provides community annotations of human lncRNAs
Homepage-2020.png
Extensively curated

Functional mechanisms and their associated lncRNAs' counts are listed below.


How to Cite

If you use any data or information in your work, please cite the following publications.

Primary publication:

Related publication:

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