Difference between revisions of "Main Page"

Latest revision as of 10:38, 18 September 2021

Welcome to LncRNAWiki 1.0

106,063 human long non-coding RNAs inside

Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

LncRNAWiki, an important component of LncBook, provides community annotations of human lncRNAs

Featured lncRNAs

Top 10 lncRNA-associated diseases

Diseases and their associated lncRNAs' counts are listed below.

Hepatocellular cancer: 361

Colorectal cancer: 305

Lung cancer: 296

Breast cancer: 282

Oral squamous cell cancer: 234

Gastric cancer: 233

Prostate cancer: 213

B acute lymphoblastic leukemia with t(1;19)(q23;p13.3): 173

Papillary thyroid cancer: 157

Obesity: 151

Extensively curated

HOTAIR

MALAT-1

H19

MEG3

NEAT1

PVT1

GAS5

CDKN2B-AS1

HOTTIP

7SK

BANCR

BTG3-AS1

CERNA2

FLICR

GUARDIN

LINC-ROR

PINCR

PLUT

LUNAR1

SRA

KCNQ1OT1

PCGEM1

XIST

BCYRN1

TUG1

UCA1

HULC

PRNCR1

TP53COR1

PANDAR

Functional mechanism

Functional mechanisms and their associated lncRNAs' counts are listed below.

How to Cite

If you use any data or information in your work, please cite the following publications.

Primary publication:

LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs. (2015) Nucleic Acids Research, 43:D187-92.

Related publication:

Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook. Curr Protoc Bioinformatics 2019.

Visitor Statistics

@@ Line 2: / Line 2: @@
 __NOTOC__
 __NOEDITSECTION__
 <!-----------------title--------------------->
 {|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
-|style="width:50%; text-align:center; white-space:nowrap; color:#000"|
+|style="width:40%; text-align:center; white-space:nowrap; color:#000"|
-<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div>
+<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki 1.0</div>
-<div style="padding:0em; font-size:100%">[http://bigd.big.ac.cn/lncbook/lncrnas 290,405] human long non-coding RNAs inside</div>
+<div style="padding:0em; font-size:100%">[[:Category:Transcripts|106,063]] human long non-coding RNAs inside</div>
-|style="width:18%;|
+|style="width:15%;|
-*[http://bigd.big.ac.cn/lncbook/lncrnas Transcripts]
+*[[:Category:Transcripts|Transcripts]]
-*[http://bigd.big.ac.cn/lncbook/featuredlncrna Featured LncRNAs]
+*[[:Category:Genes|Genes]]
-|style="width:18%;|
+*[[LncRNAWiki:Classification|Classification]]
-*[http://bigd.big.ac.cn/lncbook/disease Disease]
+|style="width:15%;|
-*[http://bigd.big.ac.cn/lncbook/function Function]
+*[[LncRNAWiki:Featured|Featured LncRNAs]]
-|style="width:18%;|
+*[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&biological_context=Disease Disease]
+*[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism= Function]
+|style="width:15%;|
+*[[LncRNAWiki:Small_proteins|Small Proteins]]
 *[http://bigd.big.ac.cn/lgc Prediction]
 *[http://bigd.big.ac.cn/lncbook/blast BLAST]
+|style="width:15%;|
+<div style="padding:0.5em 0.5em;">[[File:News2.png|center|150px|link=https://ngdc.cncb.ac.cn/lncrnawiki/]]</div>
 |}
 <!---------------welcome Box----------------->
 {|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
@@ Line 25: / Line 30: @@
 <div style="padding:1em 0.5em;">
 {{LncRNAWiki:Summary}}
-<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an import component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
+<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an important component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
 </div>
 |}
@@ Line 35: / Line 40: @@
 <!-----------Featured lncRNAs------------>
 |valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
-<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://bigd.big.ac.cn/lncbook/featuredlncrna '''Featured lncRNAs''']</div>
+<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://lncrna.big.ac.cn/index.php/LncRNAWiki:Featured Featured lncRNAs]</div>
+<div style="padding:0.5em 0.5em;">[[File:Homepage-2020.png|center|500px|link=LncRNAWiki:Featured]]</div>
+|style="padding:0px 4px;"|
+<!-----------Top 10 lncRNA-associated diseases------------>
+|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
+<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&biological_context=Disease lncRNA-associated diseases]</div>
 <div style="padding:0.5em 0.5em;">
-<table>
+''Diseases and their associated lncRNAs' counts are listed below.''
-<tr>
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=hepatocellular%20cancer Hepatocellular cancer]: 361
-<td>[[File:Featured-2018.png|left|430px|link=LncRNAWiki:Featured]]</td>
-<td valign="top">
-Extensively curated:
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=colorectal%20cancer Colorectal cancer]: 305
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=lung%20cancer Lung cancer]: 296
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=breast%20cancer Breast cancer]: 282
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=oral%20squamous%20cell%20cancer Oral squamous cell cancer]: 234
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=Gastric%20cancer Gastric cancer]: 233
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=prostate%20cancer Prostate cancer]: 213
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=b%20acute%20lymphoblastic%20leukemia%20with%20t B acute lymphoblastic leukemia with t(1;19)(q23;p13.3)]: 173
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=papillary%20thyroid%20cancer Papillary thyroid cancer]: 157
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=obesity Obesity]: 151
+</div>
+|}
+<!--------------main part two---------------->
+{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
+|-
+<!-----------------Extensively curated---------------------->
+|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
+{|style="width:100%;"
+<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Extensively curated</div>
+|style="width:33%;|
+* [[NONHSAT028508|''HOTAIR'']]
+* [[ENST00000534336.1|''MALAT-1'']]
+* [[NONHSAT017465|''H19'']]
+* [[NONHSAT039745|''MEG3'']]
+* [[ENST00000501122.2|''NEAT1'']]
+* [[ENST00000513868.2|''PVT1'']]
+* [[NONHSAT007663|''GAS5'']]
+* [[Lnc-C9orf53-2:1|''CDKN2B-AS1'']]
+* [[NONHSAT119717|''HOTTIP'']]
+* [[NONHSAT113149|''7SK'']]
+|style="width:33%;|
 * [[BANCR|''BANCR'']]
@@ Line 58: / Line 121: @@
 * [[PLUT|''PLUT'']]
-* [[SMILR|''SMILR'']]
 * [[LUNAR1|''LUNAR1'']]
+* [[Lnc-SRA1-1:1|''SRA'']]
-</td>
+|style="width:34%;|
-</tr>
+* [[NONHSAT017524|''KCNQ1OT1'']]
-</table>
-</div>
-|style="padding:0px 4px;"|
-<!-----------Top 10 lncRNA-associated diseases------------>
-|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
-<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [http://bigd.big.ac.cn/lncbook/disease lncRNA-associated diseases]</div>
-<div style="padding:0.5em 0.5em;">
-''Diseases and their associated lncRNAs' counts are listed below.''
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Neoplasms Neoplasms]: 1,077
+* [[NONHSAT076153|''PCGEM1'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Digestive%20System%20Diseases Digestive System Diseases]: 427
+* [[NONHSAT137541|''XIST'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Male%20Urogenital%20Diseases Male Urogenital Diseases]: 117
+* [[Lnc-EPCAM-1:2|''BCYRN1'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Female%20Urogenital%20Diseases%20and%20Pregnancy%20Complications Female Urogenital Diseases and Pregnancy Complications]: 196
+* [[NONHSAT084827|''TUG1'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Respiratory%20Tract%20Diseases Respiratory Tract Diseases]: 224
+* [[Lnc-OR10H5-1:1|''UCA1'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Skin%20and%20Connective%20Tissue%20Diseases Skin and Connective Tissue Diseases]: 165
+* [[NONHSAT107640|''HULC'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Endocrine%20System%20Diseases Endocrine System Diseases]: 129
+* [[NONHSAT129019|''PRNCR1'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Cardiovascular%20Diseases Cardiovascular Diseases]: 155
+* [[TP53COR1|''TP53COR1'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Congenital,%20Hereditary,%20and%20Neonatal%20Diseases%20and%20Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities]: 150
+* [[Lnc-CDKN1A-1:1|''PANDAR'']]
-* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Nervous%20System%20Diseases Nervous System Diseases]: 103
-</div>
 |}
+|style="padding:0px 4px;"|
-<!--------------main part two---------------->
+<!-----------------Function---------------------->
-{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
+|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
-|-
+<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism= Functional mechanism]</div>
-<!-----------------Small proteins---------------------->
-|valign="top" style="border:1px solid #66B3FF; background-color:transparent;45%;"|
-<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Small_proteins|Small proteins]]</div>
-<div style="padding:0.5em 0.5em;">[[File:SmallPRO-5.png|center|220px|link=LncRNAWiki:Small_proteins]]</div>
-* [[LncRNAWiki:Small_proteins|'''9,387''']] lncRNAs potentially encoding small proteins
-* '''2,246''' small proteins identified with high confidence, by considering protein instability, secondary structure and transmembrane helix
+<div style="padding:0.5em 0.5em;">
+''Functional mechanisms and their associated lncRNAs' counts are listed below.''
-|style="padding:0px 4px;"|
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=ceRNA ceRNA]:	194
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Transcriptional%20regulation Transcriptional regulation]:	85
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Epigenetic%20regulation Epigenetic regulation]:	84
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Post-transcriptional%20regulation Post-transcriptional regulation]:	12
+* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Translational%20regulation Translational regulation]:	2
-<!-----------------Classification---------------------->
-|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:54.5%;"|
+</div>
-<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Classification|Classification]]</div>
-<div style="padding:0.5em 0.5em;">[[File:Classification.png|center|400px|link=LncRNAWiki:Classification]]</div>
 |}
@@ Line 133: / Line 178: @@
 * [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
-Related publications:
+Related publication:
-* [https://www.ncbi.nlm.nih.gov/pubmed/29036542 '''Database Resources of the BIG Data Center in 2018'''.] ''Nucleic Acids Research 2018''.
+* [https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpbi.82 '''Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook'''.] '' Curr Protoc Bioinformatics 2019''.
-* [http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1060.full '''The BIG Data Center: from deposition to integration to translation'''.] (2017) ''Nucleic Acids Research'', 45:D18-24.
-* [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 '''On the classification of long non-coding RNAs'''.] (2013) ''RNA Biology'', 10:924-933.
 </div>

Difference between revisions of "Main Page"

Latest revision as of 10:38, 18 September 2021

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