Difference between revisions of "Main Page"

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{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
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|style="width:50%; text-align:center; white-space:nowrap; color:#000"|
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<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div>
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<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki 1.0</div>
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<div style="padding:0em; font-size:100%">[[Special:Categories|52,616]] human long non-coding RNAs inside</div>
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<div style="padding:0em; font-size:100%">[[:Category:Transcripts|106,063]] human long non-coding RNAs inside</div>
  
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<!---
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*[[:Category:Transcripts|Transcripts]]
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*<span class=plainlinks>[[:Category:Genes|Genes]]</span>
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*[[:Category:Genes|Genes]]
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*[[RiceWiki:GeneFamilies|Gene Families]]
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*[[LncRNAWiki:Classification|Classification]]
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|style="width:18%;|
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|style="width:15%;|
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*[[RiceWiki:Databases|Databases]]
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*[[LncRNAWiki:Featured|Featured LncRNAs]]
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*[[Special:ListUsers|Registered Users]]
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*[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&biological_context=Disease Disease]
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*[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism= Function]
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*[[RiceWiki:Templates|Templates]]
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|style="width:15%;|
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--->
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*[[LncRNAWiki:Small_proteins|Small Proteins]]
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*[http://bigd.big.ac.cn/lgc Prediction]
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*[http://bigd.big.ac.cn/lncbook/blast BLAST]
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|style="width:15%;|
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<div style="padding:0.5em 0.5em;">[[File:News2.png|center|150px|link=https://ngdc.cncb.ac.cn/lncrnawiki/]]</div>
 
|}
 
|}
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<!---------------welcome Box----------------->
 
<!---------------welcome Box----------------->
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
|valign="top" style="border:1px solid #c6c6c6; background-color:transparent; width:100%;"|
 
|valign="top" style="border:1px solid #c6c6c6; background-color:transparent; width:100%;"|
 
<div style="background:#f1f1f1; border-bottom:1px solid #c6c6c6; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Introduction</div>
 
<div style="background:#f1f1f1; border-bottom:1px solid #c6c6c6; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Introduction</div>
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<div style="padding:0.5em 0.5em;">LncRNAWiki is a wiki-based database for management of human lncRNAs, aiming to harness collective intelligence to collect, edit, and annotate information about human lncRNAs. This database is a publicly editable and open-content platform for community curation of human lncRNAs, bearing the potential to become a comprehensive and up-to-date knowledge base for human lncRNAs.
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<div style="padding:1em 0.5em;">
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{{LncRNAWiki:Summary}}
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<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an important component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
 
</div>
 
</div>
 
|}
 
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|-
 
|-
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<!-----------Data sources------------>
 
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent; width:40%;"|
 
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Data sources</div>
 
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<div style="padding:0.5em 0.5em;">LncRNAs in present database are collected from GENCODE V15, NONCODE V3, LNCipedia V2.1, and LncRNAdb (downloaded on Feb. 21st, 2013).
 
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<font color="Red">'''The update based on GENCODE V19 and NONCODE V4.0 is coming...'''</font>
 
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<br />
 
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[[File:Data source.png|center|300px]]</div><br />
 
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<div style="text-align:center">'''Note: Purple indicates LncRNAdb.'''</div>
 
  
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<!-----------------Classification---------------------->
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<!-----------Featured lncRNAs------------>
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|style="padding:0px 5px;"|
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://lncrna.big.ac.cn/index.php/LncRNAWiki:Featured Featured lncRNAs]</div>
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<div style="padding:0.5em 0.5em;">[[File:Homepage-2020.png|center|500px|link=LncRNAWiki:Featured]]</div>
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|style="padding:0px 4px;"|
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<!-----------Top 10 lncRNA-associated diseases------------>
 
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div>
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&biological_context=Disease lncRNA-associated diseases]</div>
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<div style="padding:0.5em 0.5em;">
 
<div style="padding:0.5em 0.5em;">
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There is no standard classification of lncRNA at present, and the classification of lncRNA based on genomic location is suggested to be of great biological significance (Ma etal. 2013, RNA Biology). <br />
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''Diseases and their associated lncRNAs' counts are listed below.''
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We classified lncRNAs into four groups ('''Intergenic''', '''Intronic''', '''Sense''' and '''Antisense''') based on their genomic location in respect to protein-coding genes. As it is more complicated for the condition of sense and antisense, we also listed different kinds of sense and antisense lncRNAs, which can be viewed through different categories. <br />
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=hepatocellular%20cancer Hepatocellular cancer]: 361
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[[File:web-figure2.png|center|400px]]
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=colorectal%20cancer Colorectal cancer]: 305
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=lung%20cancer Lung cancer]: 296
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=breast%20cancer Breast cancer]: 282
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=oral%20squamous%20cell%20cancer Oral squamous cell cancer]: 234
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=Gastric%20cancer Gastric cancer]: 233
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=prostate%20cancer Prostate cancer]: 213
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=b%20acute%20lymphoblastic%20leukemia%20with%20t B acute lymphoblastic leukemia with t(1;19)(q23;p13.3)]: 173
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=papillary%20thyroid%20cancer Papillary thyroid cancer]: 157
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&context_detail=obesity Obesity]: 151
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</div>
 
</div>
 
|}
 
|}
  
 
<!--------------main part two---------------->
 
<!--------------main part two---------------->
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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|-
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<!-----------------Extensively curated---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
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{|style="width:100%;"
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Extensively curated</div>
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|style="width:33%;|
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* [[NONHSAT028508|''HOTAIR'']]
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* [[ENST00000534336.1|''MALAT-1'']]
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* [[NONHSAT017465|''H19'']]
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* [[NONHSAT039745|''MEG3'']]
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* [[ENST00000501122.2|''NEAT1'']]
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* [[ENST00000513868.2|''PVT1'']]
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* [[NONHSAT007663|''GAS5'']]
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* [[Lnc-C9orf53-2:1|''CDKN2B-AS1'']]
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* [[NONHSAT119717|''HOTTIP'']]
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* [[NONHSAT113149|''7SK'']]
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|style="width:33%;|
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* [[BANCR|''BANCR'']]
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* [[BTG3-AS1|''BTG3-AS1'']]
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* [[CERNA2|''CERNA2'']]
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* [[FLICR|''FLICR'']]
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* [[GUARDIN|''GUARDIN'']]
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* [[LINC-ROR|''LINC-ROR'']]
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* [[PINCR|''PINCR'']]
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* [[PLUT|''PLUT'']]
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* [[LUNAR1|''LUNAR1'']]
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* [[Lnc-SRA1-1:1|''SRA'']]
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|style="width:34%;|
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* [[NONHSAT017524|''KCNQ1OT1'']]
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* [[NONHSAT076153|''PCGEM1'']]
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* [[NONHSAT137541|''XIST'']]
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* [[Lnc-EPCAM-1:2|''BCYRN1'']]
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* [[NONHSAT084827|''TUG1'']]
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* [[Lnc-OR10H5-1:1|''UCA1'']]
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* [[NONHSAT107640|''HULC'']]
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* [[NONHSAT129019|''PRNCR1'']]
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* [[TP53COR1|''TP53COR1'']]
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* [[Lnc-CDKN1A-1:1|''PANDAR'']]
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|}
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|style="padding:0px 4px;"|
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<!-----------------Function---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism= Functional mechanism]</div>
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<div style="padding:0.5em 0.5em;">
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''Functional mechanisms and their associated lncRNAs' counts are listed below.''
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=ceRNA ceRNA]: 194
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Transcriptional%20regulation Transcriptional regulation]: 85
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Epigenetic%20regulation Epigenetic regulation]: 84
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Post-transcriptional%20regulation Post-transcriptional regulation]: 12
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* [https://ngdc.cncb.ac.cn/lncrnawiki/browse?flag=True&functional_mechanism=Translational%20regulation Translational regulation]: 2
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</div>
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|}
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<!--------------main part three---------------->
 
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<!------------- Participating---------------->
 
<!------------- Participating---------------->
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Publications</div>
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">How to Cite</div>
 
<div style="padding:0.5em 1em;">
 
<div style="padding:0.5em 1em;">
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* [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 On the classification of long non-coding RNAs.] (2013) ''RNA Biology'', 10(6),924-933.
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If you use any data or information in your work, please cite the following publications.
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</div>
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Primary publication:
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* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
  
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<!-------------Lab Information-------------->
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Related publication:
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* [https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpbi.82 '''Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook'''.] '' Curr Protoc Bioinformatics 2019''.
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">About Us</div>
 
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<div style="padding:0.5em 1em;">Our group works in the field of [http://cbb.big.ac.cn Computational Biology and Bioinformatics] (CBB), currently with a particular focus on building biological knowledge wikis in aid of community curation of massive biological knowledge.
 
 
</div>
 
</div>
  

Latest revision as of 10:38, 18 September 2021



Welcome to LncRNAWiki 1.0
106,063 human long non-coding RNAs inside
News2.png
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

LncRNAWiki, an important component of LncBook, provides community annotations of human lncRNAs
Homepage-2020.png
Extensively curated

Functional mechanisms and their associated lncRNAs' counts are listed below.


How to Cite

If you use any data or information in your work, please cite the following publications.

Primary publication:

Related publication:

Visitor Statistics

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