DBAASP: database of antimicrobial activity and structure of peptides.

Giorgi Gogoladze, Maia Grigolava, Boris Vishnepolsky, Mindia Chubinidze, Patrice Duroux, Marie-Paule Lefranc, Malak Pirtskhalava
Author Information
  1. Giorgi Gogoladze: Laboratory of Bioinformatics, Ivane Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia.

Abstract

The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is a manually curated database for those peptides for which antimicrobial activity against particular targets has been evaluated experimentally. The database is a depository of complete information on: the chemical structure of peptides; target species; target object of cell; peptide antimicrobial/haemolytic/cytotoxic activities; and experimental conditions at which activities were estimated. The DBAASP search page allows the user to search peptides according to their structural characteristics, complexity type (monomer, dimer and two-peptide), source, synthesis type (ribosomal, nonribosomal and synthetic) and target species. The database prediction algorithm provides a tool for rational design of new antimicrobial peptides. DBAASP is accessible at http://www.biomedicine.org.ge/dbaasp/.

Keywords

MeSH Term

Algorithms
Anti-Infective Agents
Antimicrobial Cationic Peptides
Databases, Factual
Peptides

Chemicals

Anti-Infective Agents
Antimicrobial Cationic Peptides
Peptides

Word Cloud

Created with Highcharts 10.0.0databasepeptidesantimicrobialactivityDBAASPtargetstructurespeciespeptideactivitiessearchtypeDatabaseAntimicrobialActivityStructurePeptidesmanuallycuratedparticulartargetsevaluatedexperimentallydepositorycompleteinformationon:chemicalobjectcellantimicrobial/haemolytic/cytotoxicexperimentalconditionsestimatedpageallowsuseraccordingstructuralcharacteristicscomplexitymonomerdimertwo-peptidesourcesynthesisribosomalnonribosomalsyntheticpredictionalgorithmprovidestoolrationaldesignnewaccessiblehttp://wwwbiomedicineorgge/dbaasp/DBAASP:haemolytic/cytotoxic

Similar Articles

Cited By