DBAASP: database of antimicrobial activity and structure of peptides.

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Giorgi Gogoladze, Maia Grigolava, Boris Vishnepolsky, Mindia Chubinidze, Patrice Duroux, Marie-Paule Lefranc, Malak Pirtskhalava

Author Information

Giorgi Gogoladze: Laboratory of Bioinformatics, Ivane Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia.

PMID: 24888447 DOI: 10.1111/1574-6968.12489

The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is a manually curated database for those peptides for which antimicrobial activity against particular targets has been evaluated experimentally. The database is a depository of complete information on: the chemical structure of peptides; target species; target object of cell; peptide antimicrobial/haemolytic/cytotoxic activities; and experimental conditions at which activities were estimated. The DBAASP search page allows the user to search peptides according to their structural characteristics, complexity type (monomer, dimer and two-peptide), source, synthesis type (ribosomal, nonribosomal and synthetic) and target species. The database prediction algorithm provides a tool for rational design of new antimicrobial peptides. DBAASP is accessible at http://www.biomedicine.org.ge/dbaasp/.

antimicrobial activity antimicrobial peptide database haemolytic/cytotoxic activity

Algorithms

Anti-Infective Agents

Antimicrobial Cationic Peptides

Databases, Factual

Peptides

Anti-Infective Agents

Antimicrobial Cationic Peptides

Peptides

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Database Commons: DBC001661 (DBAASP)

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