CPGV   a database for Cancer Peripheral blood Gene Variations

        CPGV (Cancer Peripheral Blood Gene Variations), a public database dedicated to collecting, displaying and analyzing 496 germline variants and 11,232 somatic mutations detected in leukocytes and cfDNA of 16,659 patients with cancer from 27 cancer types. Using this database, users can retrieve the germline variants and somatic mutations of each gene across multiple cancers, review the mutation characteristics of each cancer type, and compare the differences in cfDNA profiles among different cancers and in mutations between cfDNA and tumor tissues derived from TCGA (The Cancer Genome Atlas), between somatic and germline mutations, and between cfDNA and CASPMI (a non-tumor reference cohort). The pan-cancer mutation spectrum from cfDNA provides a valuable resource for the investigation of early tumor diagnosis and treatment.