Find the related traits for input probes Ranking traits based on co-occurrence with sets of DNAm variations can provide researchers more information for their studies. All traits-associated DNAm variation sets are curated from publication and store in EWAS Atlas.
Find the related traits for input trait Typically, there are many causal link between different traits. If two traits are done by similar set of related DNAm variations, the traits might be have a relationship. This search function is to identify the related traits by quantitatively measuring the degree of the agreement how traits share the similar participating DNAm variations.
Usage Input:
Probe ID of 850K/450K/27K
Trait in EWAS Atlas
Mode:
Global traits mode In this mode, a modified Fisher's exact test is used to examine significance of association between input probes and traits-associated probe lists in EWAS Atlas.
Custom traits mode Users can customize a set of traits, and use modified Fisher's exact test to perform an association analysis between a set of input probes and custom traits associated probes, detecting whether the input probe is associated with the custom traits.
Output:
Trait: The detected phenotype
-log10 (p): The converted p-value of modified fisher test
Count: Probes involved in the term
Percentage: Involved probes/total probes associated with this trait
We also provide the full list of trait-trait enrichment as download page.