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HRA001033
   HRA001033.xlsx
Title:
Single-cell RNA-seq and bulk RNA data of non-small cell lung cancer during neoadjuvant immunotherapy
Release date:
2023-01-28
Description:
Most patients are still refractory to immunotherapy or acquire resistance. We characterized the single-cell transcriptomes of ~92000 cells from 15 non-small cell lung cancer (NSCLC) before and after neoadjuvant PD-1 blockade combined with chemotherapy to decode immunotherapy resistance mechanisms. In addition, we also performed bulk RNA-seq from another 24 patients before therapy as a validation cohort. Our study offers invaluable resources for uncovering immunotherapy resistance.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA005740
Study type:
Disease Study
Disease name:
non-small cell lung carcinoma
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC000619
DAC name:
transcriptomic for NSCLC
Contact person:
Zhang Peng
Email:
zhangpeng1121@tongji.edu.cn
Description:
We single-cell RNA-seq from 15 non-small cell lung cancer (NSCLC) before and after neoadjuvant PD-1 blockade combined with chemotherapy to decode immunotherapy resistance mechanisms. In addition, we also performed bulk RNA-seq from another 24 patients before therapy as a validation cohort.
Individuals & samples
Files
Request Data
Submitter:   Zhang Peng / zhangpeng1121@tongji.edu.cn
Organization:   Shanghai Pulmonary Hospital Tongji University
Submission date:   2021-07-06
Requests:   25