e.g., HRA000087; HRA000150
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HRA006885
   HRA006885.xlsx
Title:
Single-Cell and Spatial Analyses Reveal Tertiary Lymphoid Structures Linked to Tumour Progression and Immunotherapy Response in Nasopharyngeal Carcinoma
Release date:
2024-07-01
Description:
Here, we revealed the composition of TLSs in NPC, by analysing the single-cell and spatial transcriptional profiles. We identified TLS-associated cell subpopulations (germinal centre B, CD4+ T follicular helper, CXCL13+TCF7+CD8+ T cells, and CXCL13+ fibroblasts) in NPC. Moreover, TLS-associated signatures predicted better prognosis and were correlated with immunotherapy outcomes in independent NPC cohorts.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA009213
Study type:
Disease Study
Disease name:
nasopharynx carcinoma
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC000101
DAC name:
BEL_LAB
Contact person:
BEI JINXIN
Email:
beijx@sysucc.org.cn
Description:
SYSUCC
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Submitter:   BEI JINXIN / beijx@sysucc.org.cn
Organization:   Sun Yat-sen University Cancer Center
Submission date:   2022-04-12
Requests:   10