Online Tools

Build Phylogenetic Tree using maximum likelihood method by IQ-TREE or RAxML for the submitted sequences.
The default workflow: ① Input: the submitted SARS-CoV-2 genome sequences; ② Trim Method: excluding the 5’ and 3’ untranslated regions based on SARS-CoV-2 reference genome (NC_045512.2); ③ Substitution Model: Use ModelFinder in IQ-TREE (Use GTRGAMMA in RAxML); ④ Unused Bootstrap test. Customizable parameters: Input sequence type; Trim Method (refseq, TrimAl, None); Software (IQ-TREE or RAxML); Substitution Model; bootstrap (IQ-TREE can also choose UFBoot - Ultrafast Bootstrap Approximation)