beta-Adrenergic stimulation of respiratory ciliary activity.

P Verdugo, N T Johnson, P Y Tam

Author Information

PMID: 7451296 DOI: 10.1152/jappl.1980.48.5.868

We investigated the effect of isoproterenol on ciliary activity using a mucus-free preparation of cultured ciliated cells of the rabbit trachea. The frequency of ciliary beating was monitored by dynamic laser-scattering spectroscopy. The results demonstrated that isoproterenol directly stimulates the activity of ciliated cells of the respiratory epithelium and that this effect is beta-adrenergic specific inasmuch as the observed stimulation can be blocked by propranolol.

HL-20191-03/NHLBI NIH HHS

Animals

Cilia

Isoproterenol

Lasers

Propranolol

Rabbits

Trachea

Propranolol

Isoproterenol

Journal Article Research Support, U.S. Gov't, P.H.S.

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