OpenLB
Open Library of Bioscience
Advanced Search
Neurology
01 03, 2017;88 (1): 101-102.

Ibrutinib monotherapy in relapsed/refractory CNS lymphoma: A retrospective case series.

Kamal Chamoun, Sylvain Choquet, Eileen Boyle, Caroline Houillier, Delphine Larrieu-Ciron, Ahmad Al Jijakli, Vanessa Delrieu, Vincent Delwail, Franck Morschhauser, Khê Hoang-Xuan, Carole Soussain
Author Information
  1. Kamal Chamoun: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  2. Sylvain Choquet: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  3. Eileen Boyle: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  4. Caroline Houillier: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  5. Delphine Larrieu-Ciron: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  6. Ahmad Al Jijakli: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  7. Vanessa Delrieu: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  8. Vincent Delwail: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  9. Franck Morschhauser: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  10. Khê Hoang-Xuan: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium.
  11. Carole Soussain: From the French LOC Network for PCNSL, Hôpital René Huguenin-Institut Curie (K.C., C.S.), Saint-Cloud; French LOC Network for PCNSL, GH Pitié-Salpêtrière (S.C., C.H., K.H.-X.), Paris; French LOC Network for PCNSL, CHU Lille (E.B., F.M.); French LOC Network for PCNSL, CH Potiers (D.L.-C., V.D.); French LOC Network for PCNSL, CH Argenteuil (A.A.J.), France; and Université Libre de Belgiques (V.D.), Brussels, Belgium. carole.soussain@curie.fr.
PMID: 27864520 DOI: 10.1212/WNL.0000000000003420

Abstract

No abstract text available.

MeSH Term

Adenine
Aged
Antineoplastic Agents
Central Nervous System Neoplasms
Female
Follow-Up Studies
Humans
International Cooperation
Lymphoma
Magnetic Resonance Imaging
Male
Middle Aged
Neoplasm Recurrence, Local
Piperidines
Pyrazoles
Pyrimidines
Retrospective Studies

Chemicals

Antineoplastic Agents
Piperidines
Pyrazoles
Pyrimidines
ibrutinib
Adenine
Journal Article Multicenter Study
Article has an altmetric score of 8

Word Cloud

Created with Highcharts 10.0.0Ibrutinibmonotherapyrelapsed/refractoryCNSlymphoma:retrospectivecaseseries

Similar Articles

Cited By (30)

Combination of ibrutinib and chemotherapy produced a durable remission in multiply relapsed diffuse large B-cell lymphoma leg type with mutant and wildtype .Diagnosing, imaging, and successfully treating a debilitating case of Bing-Neel syndrome: A multidisciplinary feat.Rituximab, methotrexate, procarbazine, vincristine and intensified cytarabine consolidation for primary central nervous system lymphoma (PCNSL) in the elderly: a LOC network study.Experience with nasogastric tube administration of tirabrutinib in the treatment of an elderly patient with primary central nervous system lymphoma.Use of rituximab, temozolomide, and radiation in recurrent and refractory primary central nervous system lymphoma in the Philippines: a retrospective analysis.Preliminary Evaluation of Zanubrutinib-Containing Regimens in DLBCL and the Cerebrospinal Fluid Distribution of Zanubrutinib: A 13-Case Series.Primary Central Nervous System Lymphoma: Long-Term Treatment Outcomes and Cost-Analysis from a Retrospective Study of High-Dose Methotrexate Based Chemoimmunotherapy and Reduced Dose Radiation Therapy Approach.Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma.Ibrutinib in Refractory or Relapsing Primary Central Nervous System Lymphoma: A Systematic Review.Efficacy and Safety of Ibrutinib as Monotherapy or Combination Therapy in Relapsed/Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL): A Systematic Review and Meta-analysis.
See all "Cited by" articles