Disease Ontology ID: DDTO:0000841
Disease Description: A condition where the optic nerve going from the eye to the brain is too small.
Inherit Mode: The mode of inheritance is unclear.
Disease Symptom: Depending on the degree of hypoplasia (underdevelopment), an eye may be partially or completely blind. Usually if only one eye is affected, your dog will compensate for the decreased vision to the point that you are unaware of any abnormality. You may notice that the pupils of your dog's eyes are different sizes - the pupil of the affected eye will be larger. If both eyes are affected, your dog will have some loss of sight or will be blind.
Disease Cause: -
Disease Diagnose: This condition is suspected when a dog is visually impaired from birth. Based on clinical and ophthalmoscopic examination, your veterinarian will determine if optic nerve hypoplasia is the cause. This condition must be distinguished from micropapilla, a normal variation of optic disc appearance where the disc is smaller but vision is normal.
Treat Method: There is no treatment. With their acute senses of smell and hearing, dogs can manage well despite reduced vision. You can help your visually impaired dog by developing regular routes for exercise, maintaining your dog's surroundings as consistently as possible, introducing any necessary changes gradually, and being patient.
Breeder Advice: Affected dogs and close relatives should not be used for breeding.
Disease Description Source: Link
Disease Name | Other Name | Mode of inheritance | Link ID | Possible OMIM ID | Gene |
---|---|---|---|---|---|
Optic nerve hypoplasia, bilateral | - | - | - |
iDog Breed Number | Breed Name | Personality | Height | Weight | Breed Source |
---|---|---|---|---|---|
CB83 | Dachshund | Friendly, Curious, Spunky | 20.3-22.9 cm (standard), 12.7-15.2 cm (miniature) | 7.3-14.5 kg (standard), 5 kg & under (miniature) | Germany |
CB110 | German Shepherd Dog | Smart, confident, courageous, and steady; a true dog lover's dog | 61-66 cm (male), 55.9-61 cm (female) | 29.5-40.8 kg (male), 22.7-31.8 kg (female) | Germany |
CB120 | Great Pyrenees | Calm, patient, smart; strong-willed yet affectionate | 68.6-81.3 cm (male), 63.5-73.7 cm (female) | 45.4 kg & up (male), 38.6 kg & up (female) | France, Spain |
CB131 | Irish Setter | Outgoing, sweet-natured, active, and trainable | 68.6 cm (male), 63.5 cm (female) | 31.8 kg (male), 27.2 kg (female) | Ireland |
CB161 | Miniature Schnauzer | Friendly, smart, obedient | 30.5-35.6 cm | 5-9.1 kg | Germany |
CB167 | Norfolk Terrier | Alert, fearless, fun-loving, and more sociable than the usual terrier | 22.9-25.4 cm | 5-5.4 kg | United Kingdom |
CB232 | St. Bernard | Friendly, patient, outgoing; known as a great “nanny dog” for kids | 71.1-76.2 cm (males), 66-71.1 cm (female) | 63.5-81.6 kg (male), 54.4-63.5 kg (female) | Italy, Switzerland |
CB268 | Miniature Poodle | Intelligent, Eager-to-please , Charming companion | 25-38 cm | 4.5-6.8kg | France&Germany |
CB269 | Standard Poodle | Intelligent and quick-to-please | 56-66 cm | ||
CB270 | Toy Poodle | Intelligent, eager to please, quick to learn and an affectionate, loyal pet. | under 25 cm | ||
CB25 | Bearded Collie | Bouncy, charismatic, friendly; smart, but also stubborn and independent | 53.3-55.9 cm (male), 50.8-53.3 cm (female) | 20.4-24.9 kg | United Kingdom (Scotland) |
CB80 | Coton de Tulear | Bright, happy-go-lucky, endlessly charming; born to love and to be loved | 25.4-27.9 cm (male), 22.9-25.4 cm (female) | 4.1-6.8 kg (male), 3.6-5.9 kg (female) | Madagascar |
CB98 | English Toy Spaniel | Affectionate, Alert, Merry | 22.9-25.4 cm | 3.6-6.4 kg | England |
CB111 | German Short-Haired Pointer | Friendly, smart, willing to please | 58.4-63.5 cm (male), 53.3-58.4 cm (female) | 24.9-31.8 kg (male), 20.4-27.2 kg (female) | Germany |
CB117 | Gordon Setter | Bold, confident, and resolute afield; sweetly affectionate by the fireside | 61-68.6 cm (male), 58.4-66 cm (female) | 24.9-36.3 kg (male), 20.4-31.8 kg (female) | United Kingdom (Scotland) |
CB123 | Hamiltonstovare(Hamilton Hound) | Agile, Versatile, Regal | 53-61cm (male) 49-57cm (female) | 18-26kg | Sweden |
CB132 | Irish Terrier | Bold, dashing, even reckless; stouthearted at work, tenderhearted at home | 45.7 cm | 12.2 kg (male), 11.3 kg (female) | Ireland |
CB136 | German Jagdterrier | Courageous, Intelligent, Hardworking | 33-40cm | 7.7-9.9kg | Germany |
CB217 | Japanese Shiba Inu | Alert, active, and attentive | 35.6-43.2 cm (male), 33-40.6 cm (female) | 8.2-10.9 kg (male), 6.8-9.1 kg (female) | Japan |
CB229 | Spanish Mastiff | Aloof, dignified, calm and intelligent | Spain | ||
CB183 | Pharaoh Hound | Smart and alert; noble, but friendly and affectionate | 58.4-63.5 cm (male), 53.3-61 cm (female) | 20.4-24.9 kg | Malta |
2008 |
daSilva,E.G.,Dubielzig,R.,Zarfoss,M.K.,Anibal,A.: :
Distinctive histopathologic features of canine optic nerve hypoplasia and aplasia: a retrospective review of 13 cases. Vet Ophthalmol 11:23-9, 2008. Pubmed reference: 18190348 . DOI: 10.1111/j.1463-5224.2007.00596.x . |
1999 |
Ackerman, L. :
The genetic connection AAHA Press p 159-160 |
1999 |
Ackerman L. :
The Genetic Connection: A Guide to Health Problemsin Purebred Dogs AAHA Press,Lakewood, Colorado p. 126 |
1998 |
Termote,S.: :
What is your diagnosis? Congenital optic nerve hypoplasia in a dog. J Small Anim Pract 39:1, 39, 1998. Pubmed reference: 9494926 . |
1981 |
Kern,T.J.,Riis,R.C.: :
Optic nerve hypoplasia in three Miniature Poodles. J Am Vet Med Assoc 178:49-54, 1981. Pubmed reference: 7204223 . |
1976 |
Ernest,J.T.: :
Bilateral optic nerve hypoplasia in a pup. J Am Vet Med Assoc 168:125-8, 1976. Pubmed reference: 1245453 . |
1971 |
Gelatt,K.N.,Leipold,H.W.: :
Case report. Bilateral optic nerve hypoplasia in two dogs. Can Vet J 12:91-6, 1971. Pubmed reference: 5104935 . |
1952 |
Saunders,L.Z.: :
Congenital optic nerve hypoplasia in Collie dogs Cornell Veterinarian 42:67-80, 1952. Pubmed reference: 14905886 . |