The detail information of Calcinosis circumscripta
Basic Information

Disease Ontology ID: DDTO:0000770

Disease Description: The development of lumps of hard calcium deposits in the skin.

Inherit Mode: -

Disease Symptom: Calcinosis circumscripta on the tongue of a dog may look like a raised and irregular yellowish-pink nodule, while on digits an ulcer may be present in the center of the lesion.

Disease Cause: -

Disease Diagnose: Diagnosis is based on histological examination of affected tissue.

Treat Method: The conventional treatment of calcinosis circumscripta involves surgical removal and is usually curative. In some cases, lesions have been observed to resolve on their own. An oral charcoal adsorbent (Kremezin) has been reported to be effective. Following this treatment, a significant decrease in the serum calcium level x the serum phosphorus level is observed, and dogs improve dramatically.

Breeder Advice: -

Disease Description Source: Link

Associated Diseases
Disease Name Other Name Mode of inheritance Link ID Possible OMIM ID Gene
Calcinosis circumscripta - - - -
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB46 Boston Terrier Friendly, bright, amusing, and adaptable. 38.1-43.2 cm 4.5-11.3 kg United States
CB111 German Short-Haired Pointer Friendly, smart, willing to please 58.4-63.5 cm (male), 53.3-58.4 cm (female) 24.9-31.8 kg (male), 20.4-27.2 kg (female) Germany
CB120 Great Pyrenees Calm, patient, smart; strong-willed yet affectionate 68.6-81.3 cm (male), 63.5-73.7 cm (female) 45.4 kg & up (male), 38.6 kg & up (female) France, Spain
CB186 Polish Lowland Shepherd Dog Lively, clever, confident; very loyal, but an independent worker 45.7-50.8 cm (male), 43.2-48.3 cm (female) 13.6-22.7 kg Poland
Associated Disease Variants from OMIA
Gene Differential Expression
References
1997 Gross,T.L.: :
Calcinosis circumscripta and renal dysplasia in a dog Veterinary Dermatology 8:27-31, 1997.
1996 Hartmann,M.,Steidl,T.,Thiel,W.: :
Bilateral calcinosis circumscripta in a german shepherd dog with additional incidence of a metastasising osteosarcoma and bilateral acropachy of the forelimbs [German] Kleintierpraxis 41:421 ff., 1996.