Disease Ontology ID: DDTO:0000374

Disease Description: A condition where the cerebellum, a part of the brain, is poorly formed (too small or absent) and doesn't function properly or at all.

Inherit Mode: Autosomal recessive. This disorder is rare. There are sporadic reports of this disorder in breeds other than those listed below.

Disease Symptom: The cerebellum is the part of the brain that regulates the control and coordination of voluntary movement. The clinical signs of cerebellar dysfunction in affected puppies range from mild to severe, and may include poor balance, a wide-based stance (feet planted far apart), stiff or high-stepping gait, apparent lack of awareness of where the feet are (standing or walking with a foot knuckled over), and head or body tremors. Affected pups have normal mental alertness. In this condition, in contrast to cerebellar abiotrophy, signs of cerebellar dysfunction are evident at birth or by 2 weeks thereafter, and do not get worse as the pup ages. Other than the abnormalities in balance and coordination, the animal's general health is unaffected.

Disease Cause: -

Disease Diagnose: The clinical signs (relating to uncoordinated movement and lack of balance) are evident as soon as the pups are walking and are suggestive of a cerebellar disorder. Your veterinarian will do tests to rule out other conditions that can cause similar signs.

Treat Method: There is no treatment for this condition. Affected dogs will not get any worse (or better) and, especially where the signs are mild, may be able to lead a relatively normal life, particularly if owners can adjust their expectations to the dog's limitations.

Breeder Advice: Affected dogs, their parents and their siblings should not be used for breeding.

Disease Description Source: Link