The detail information of Cranioschisis
Basic Information

Disease Ontology ID: DDTO:0000896

Another Name: cranial dysraphism

Disease Description: Abnormal development of the skull characterized by openings between or in the bones.

Inherit Mode: -

Disease Symptom: The skull sutures of the newborn puppy can only be felt by careful examination. Failure of sutures to close appears as "soft spots." The soft crevices can be about 1/8 inch wide and 1/4 inch long. Instead of disappearing, they become wider. The condition is lethal.

Disease Cause: Cranioschisis can result from high concentrations of retinoids which occur in some pet food formulations as a result of the use of animal liver as an ingredient.

Disease Diagnose: -

Treat Method: -

Breeder Advice: -

Disease Description Source: -

Associated Diseases
Disease Name Other Name Mode of inheritance Link ID Possible OMIM ID Gene
Cranioschisis - - - -
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB78 Cocker Spaniel Happy, smart, gentle 36.8-39.4 cm (male), 34.3-36.8 cm (female) 11.3-13.6 kg (male), 9.1-11.3 kg (female)
CB98 English Toy Spaniel Affectionate, Alert, Merry 22.9-25.4 cm 3.6-6.4 kg England
Associated Disease Variants from OMIA
Gene Differential Expression
References
1952 Pullig,T.: :
Inheritance of a skull defect in Cocker Spaniels Journal of Heredity 43:97-99, 1952.