The detail information of Bleeding disorder, P2RY12-related
OMIA Basic Information
Possible human homologues (MIM numbers):
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal Recessive
Considered a defect: yes
Year key mutation first reported: 2011
Species-specific name: ADP response impaired; Postoperative hemorrhage
Species-specific symbol: -
More detail information can see in
Associated Breeds
| iDog Breed Number | Breed Name | Personality | Height | Weight | History | Breed Source |
|---|---|---|---|---|---|---|
| CB121 | Greater Swiss Mountain Dog | 64.8-72.4 cm (male), 60.2-68.6 cm (female) | 52.2-63.5 kg (male), 38.6-49.9 kg (female) | Switzerland |
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2017 |
Flores,R.S.,Boudreaux,M.K.,Vasquez,B.,Bristow,P.,Aronson,L.R.,Santoro-Beer,K.,Callan,M.B.: :
Heterozygosity for P2Y12 receptor gene mutation associated with postoperative hemorrhage in a Greater Swiss Mountain dog. Vet Clin Pathol 46:569-574, 2017. Pubmed reference: 28800150 . DOI: 10.1111/vcp.12533 . |
| 2011 |
Boudreaux,MK.,Martin,M.: :
P2Y12 receptor gene mutation associated with postoperative hemorrhage in a Greater Swiss Mountain dog. Vet Clin Pathol 40:202-206, 2011. Pubmed reference: 21554368 . DOI: 10.1111/j.1939-165X.2011.00318.x . |