The detail information of Melanoma, malignant
OMIA Basic Information

Possible human homologues (MIM numbers): -

Mendelian trait/disorder: unknown

Mode of inheritance: -

Considered a defect: yes

Year key mutation first reported: -

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
There are associated breeds.
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Tani,H.,Miyamoto,R.,Noguchi,S.,Kurita,S.,Nagashima,T.,Michishita,M.,Yayoshi,N.,Tamura,K.,Bonkobara,M.: :
A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis. BMC Vet Res 17:147, 2021.
Pubmed reference: 33827546 . DOI: 10.1186/s12917-021-02864-3 .
2018 Jama,N.,Farquhar,N.,Butt,Z.,Coupland,S.E.,Sacco,J.J.,Scase,T.,Fielding,A.B.,Coulson,J.M.,Kalirai,H.,Killick,D.R.: :
Altered Nuclear Expression of the Deubiquitylase BAP1 Cannot be Used as a Prognostic Marker for Canine Melanoma. J Comp Pathol 162:50-58, 2018.
Pubmed reference: 30060843 . DOI: 10.1016/j.jcpa.2018.06.007 .
2016 Gramer,I.,Kessler,M.,Geyer,J.: :
Detection of novel polymorphisms in the ckit gene of canine patients with lymphoma, melanoma, haemangiosarcoma, and osteosarcoma. Vet Res Commun 40:89-95, 2016.
Pubmed reference: 26971271 . DOI: 10.1007/s11259-016-9653-x .
2013 Chu,P.Y.,Pan,S.L.,Liu,C.H.,Lee,J.,Yeh,L.S.,Liao,A.T.: :
KIT gene exon 11 mutations in canine malignant melanoma. Vet J 196:226-30, 2013.
Pubmed reference: 23069279 . DOI: 10.1016/j.tvjl.2012.09.005 .
2013 Dobson,J.M.: :
Breed-predispositions to cancer in pedigree dogs. ISRN Vet Sci 2013:941275, 2013.
Pubmed reference: 23738139 . DOI: 10.1155/2013/941275 .
2011 Murakami,A.,Mori,T.,Sakai,H.,Murakami,M.,Yanai,T.,Hoshino,Y.,Maruo,K.: :
Analysis of KIT expression and KIT exon 11 mutations in canine oral malignant melanomas. Vet Comp Oncol 9:219-24, 2011.
Pubmed reference: 21848624 . DOI: 10.1111/j.1476-5829.2010.00253.x .
2009 London,C.A.,Malpas,P.B.,Wood-Follis,S.L.,Boucher,J.F.,Rusk,A.W.,Rosenberg,M.P.,Henry,C.J.,Mitchener,K.L.,Klein,M.K.,Hintermeister,J.G.,Bergman,P.J.,Couto,G.C.,Mauldin,G.N.,Michels,G.M.: :
Multi-center, placebo-controlled, double-blind, randomized study of oral toceranib phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision. Clin Cancer Res 15:3856-65, 2009.
Pubmed reference: 19470739 . DOI: 10.1158/1078-0432.CCR-08-1860 .
2003 Sulaimon,S.S.,Kitchell,B.E.: :
The basic biology of malignant melanoma: molecular mechanisms of disease progression and comparative aspects. J Vet Intern Med 17:760-72, 2003.
Pubmed reference: 14658711 .
1992 Mayr,B.,Eschborn,U.,Schleger,W.,Loupal,G.,Burtscher,H.: :
Cytogenetic studies in a canine malignant melanoma. J Comp Pathol 106:319-22, 1992.
Pubmed reference: 1602064 .