The detail information of Chondrodysplasia
OMIA Basic Information

Possible human homologues (MIM numbers):

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal

Considered a defect: no

Year key mutation first reported: 2009

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
There are associated breeds.
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2010 Bannasch,D.,Young,A.,Myers,J.,Truvé,K.,Dickinson,P.,Gregg,J.,Davis,R.,Bongcam-Rudloff,E.,Webster,M.T.,Lindblad-Toh,K.,Pedersen,N.: :
Localization of canine brachycephaly using an across breed mapping approach. PLoS One 5:e9632, 2010.
Pubmed reference: 20224736 . DOI: 10.1371/journal.pone.0009632 .
2009 Kaessmann,H.: :
Genetics. More than just a copy. Science 325:958-9, 2009.
Pubmed reference: 19696341 . DOI: 10.1126/science.1178487 .
2009 Parker,HG.,Vonholdt,BM.,Quignon,P.,Margulies,EH.,Shao,S.,Mosher,DS.,Spady,TC.,Elkahloun,A.,Cargill,M.,Jones,PG.,Maslen,CL.,Acland,GM.,Sutter,NB.,Kuroki,K.,Bustamante,CD.,Wayne,RK.,Ostrander,EA.: :
An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. Science 325:995-8, 2009.
Pubmed reference: 19608863 . DOI: 10.1126/science.1173275 .
2008 Young,AE.,Bannasch,DL.: :
SNPS in the promoter regions of the canine RMRP and SHOX genes are not associated with canine chondrodysplasia. Anim Biotechnol 19:1-5, 2008.
Pubmed reference: 18228171 . DOI: 10.1080/10495390701638328 .
1994 Bingel,S.A.,Sande,R.D.: :
Chondrodysplasia in five Great Pyrenees Journal of the American Veterinary Medical Association 205:845-848, 1994.
Pubmed reference: 7829378 .
1975 Braund,K.G.,Ghosh,P.,Taylor,T.K.F.,Larsen,L.H.: :
Morphological studies of the canine intervertebral disc: the assignment of the Beagle to the achondroplastic classification Research in Veterinary Science 19:167-172, 1975.
Pubmed reference: 1166121 .
1952 Hansen,H.J.: :
A pathologic-anatomical study on disc degeneration in dog, with special reference to the so-called enchondrosis intervertebralis. Acta Orthop Scand Suppl 11:1-117, 1952.
Pubmed reference: 14923291 .
1951 Hansen,H.J.: :
A pathologic-anatomical interpretation of disc degeneration in dogs. Acta Orthop Scand 20:280-93, 1951.
Pubmed reference: 14894198 .